Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis

被引:18
作者
Decmann, Abel [1 ]
Perge, Pal [1 ]
Turai, Peter Istvan [1 ]
Patocs, Attila [2 ,3 ,4 ]
Igaz, Peter [1 ,5 ]
机构
[1] Semmelweis Univ, Fac Med, Dept Internal Med 2, Szentkiralyi Str 46, H-1088 Budapest, Hungary
[2] MTA SE Lendulet Hereditary Endocrine Tumors Res G, H-1089 Budapest, Hungary
[3] Semmelweis Univ, Dept Lab Med, H-1089 Budapest, Hungary
[4] Natl Inst Oncol, Dept Mol Genet, H-1122 Budapest, Hungary
[5] MTA SE Mol Med Res Grp, H-1088 Budapest, Hungary
关键词
non-coding RNA; microRNA; lncRNA; adrenocortical cancer; biomarker; GROWTH-FACTOR-II; GENOME-WIDE ANALYSIS; CIRCULATING MICRORNAS; EXPRESSION; GENE; TUMORS; TISSUE; CARCINOMA; MARKERS; SERUM;
D O I
10.3390/cancers12020461
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical cancer still remains elusive and there are no reliable blood-borne markers of adrenocortical malignancy, either. Several findings show the potential applicability of microRNAs as biomarkers of malignancy and prognosis, and there are some data on lncRNA as well. In this review, we present a synopsis on the potential relevance of non-coding RNA molecules in adrenocortical pathogenesis and their applicability in diagnosis from tissue and blood.
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页数:17
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共 99 条
  • [1] MiR-483-5p and miR-139-5p promote aggressiveness by targeting N-myc downstream-regulated gene family members in adrenocortical cancer
    Agosta, Claire
    Laugier, Jonathan
    Guyon, Laurent
    Denis, Josiane
    Bertherat, Jerome
    Libe, Rossella
    Boisson, Bruno
    Sturm, Nathalie
    Feige, Jean-Jacques
    Chabre, Olivier
    Cherradi, Nadia
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2018, 143 (04) : 944 - 957
  • [2] Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors
    Almeida, Madson Q.
    Barisson Villares Fragoso, Maria Candida
    Pacicco Lotfi, Claudimara Ferini
    Santos, Mariza Gerdulo
    Nishi, Mirian Yumie
    Soares Costa, Marcia Helena
    Lerario, Antonio Marcondes
    Maciel, Carolina Canton
    Mattos, Gabriele Ebling
    Lima Jorge, Alexander Augusto
    Mendonca, Berenice B.
    Latronico, Ana Claudia
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2008, 93 (09) : 3524 - 3531
  • [3] Research Techniques Made Simple: Identification and Characterization of Long Noncoding RNA in Dermatological Research
    Antonini, Dario
    Mollo, Maria Rosaria
    Missero, Caterina
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017, 137 (03) : E21 - E26
  • [4] Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
    Arroyo, Jason D.
    Chevillet, John R.
    Kroh, Evan M.
    Ruf, Ingrid K.
    Pritchard, Colin C.
    Gibson, Donald F.
    Mitchell, Patrick S.
    Bennett, Christopher F.
    Pogosova-Agadjanyan, Era L.
    Stirewalt, Derek L.
    Tait, Jonathan F.
    Tewari, Muneesh
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (12) : 5003 - 5008
  • [5] Gene expression profiling in adrenocortical neoplasia
    Assie, G.
    Giordano, T. J.
    Bertherat, J.
    [J]. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2012, 351 (01) : 111 - 117
  • [6] Integrated genomic characterization of adrenocortical carcinoma
    Assie, Guillaume
    Letouze, Eric
    Fassnacht, Martin
    Jouinot, Anne
    Luscap, Windy
    Barreau, Olivia
    Omeiri, Hanin
    Rodriguez, Stephanie
    Perlemoine, Karine
    Rene-Corail, Fernande
    Elarouci, Nabila
    Sbiera, Silviu
    Kroiss, Matthias
    Allolio, Bruno
    Waldmann, Jens
    Quinkler, Marcus
    Mannelli, Massimo
    Mantero, Franco
    Papathomas, Thomas
    De Krijger, Ronald
    Tabarin, Antoine
    Kerlan, Veronique
    Baudin, Eric
    Tissier, Frederique
    Dousset, Bertrand
    Groussin, Lionel
    Amar, Laurence
    Clauser, Eric
    Bertagna, Xavier
    Ragazzon, Bruno
    Beuschlein, Felix
    Libe, Rossella
    de Reynies, Aurelien
    Bertherat, Jerome
    [J]. NATURE GENETICS, 2014, 46 (06) : 607 - 612
  • [7] miRNA Processing and Human Cancer: DICER1 Cuts the Mustard
    Bahubeshi, Amin
    Tischkowitz, Marc
    Foulkes, William D.
    [J]. SCIENCE TRANSLATIONAL MEDICINE, 2011, 3 (111)
  • [8] MicroRNAs: Genomics, biogenesis, mechanism, and function (Reprinted from Cell, vol 116, pg 281-297, 2004)
    Bartel, David P.
    [J]. CELL, 2007, 131 (04) : 11 - 29
  • [9] MicroRNA Expression in Formalin-fixed Paraffin-embedded Cancer Tissue: Identifying Reference MicroRNAs and Variability
    Boisen, Mogens Karsbol
    Dehlendorff, Christian
    Linnemann, Dorte
    Schultz, Nicolai Aagaard
    Jensen, Benny Vittrup
    Hogdall, Estrid Vilma Solyom
    Johansen, Julia Sidenius
    [J]. BMC CANCER, 2015, 15
  • [10] Camussi G, 2011, AM J CANCER RES, V1, P98