Dual-mode sensing platform based on colloidal gold functionalized porous silicon

被引：44

作者：

Jiao, Yang ^{[1
]}

Koktysh, Dmitry S. ^{[2
,3
]}

Phambu, Nsoki ^{[4
]}

Weiss, Sharon M. ^{[1
,3
]}

机构：

[1] Vanderbilt Univ, Dept Elect Engn & Comp Sci, Nashville, TN 37235 USA

[2] Vanderbilt Univ, Dept Chem, Nashville, TN 37235 USA

[3] Vanderbilt Univ, Vanderbilt Inst Nanoscale Sci & Engn, Nashville, TN 37235 USA

[4] Tennessee State Univ, Dept Chem, Nashville, TN 37209 USA

来源：

APPLIED PHYSICS LETTERS | 2010年 / 97卷 / 15期

基金：

美国国家科学基金会;

关键词：

ENHANCED RAMAN-SCATTERING; MICROCAVITIES; SURFACES;

D O I：

10.1063/1.3503608

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We report a dual-mode sensing platform based on a single layer porous silicon (PSi) film impregnated with colloidal gold nanoparticles. This gold-coated PSi film supports both quantification of molecular binding via reflectance measurements and molecular identification via surface enhanced Raman scattering (SERS). A detection sensitivity of approximately 400 nm/RIU was demonstrated through binding of benzenethiol molecules. Identification of the unique SERS peaks was possible with uniform signal intensity across the sample and a detection limit below 1 mu M. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3503608]

引用

页数：3

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