Synthesis of -Ketosulfones by using Sulfonyl Chloride as a Sulfur Source

被引：37

作者：

Xia, Yingya ^{[1
]}

Chen, Xiaolan ^{[1
]}

Qu, Lingbo ^{[1
,2
]}

Sun, Kai ^{[1
]}

Xia, Xiaoyi ^{[1
]}

Fu, Wenkai ^{[1
]}

Chen, Xi ^{[1
]}

Yang, Yongkang ^{[1
]}

Zhao, Yufen ^{[1
,3
]}

Li, Chaojun ^{[4
,5
]}

机构：

[1] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450052, Peoples R China

[2] Luoyang Inst Sci & Technol, Luoyang 471023, Peoples R China

[3] Xiamen Univ, Dept Chem, Xiamen 361005, Peoples R China

[4] McGill Univ, Dept Chem, Montreal, PQ H3A 0B8, Canada

[5] McGill Univ, FQRNT Ctr Green Chem & Catalysis, Montreal, PQ H3A 0B8, Canada

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 5卷 / 07期

关键词：

alkenes; electrophiles; -ketosulfones; sulfonyl chlorides; BETA-KETO-SULFONES; DEHYDROGENASE TYPE-I; ONE-POT SYNTHESIS; IONIC LIQUID; EFFICIENT; DERIVATIVES; INHIBITORS; DIOXYGEN; STRATEGY; ALKYNES;

D O I：

10.1002/ajoc.201600205

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient one-pot green strategy has been developed for the synthesis of -ketosulfones by directly using easily available and inexpensive sulfonyl chlorides as a sulfur source to react with aromatic alkenes in the presence of cheap tert-butyl hydroperoxide (TBHP) and Et3N in 1,2-dichloroethane (DCE) at 45 degrees C within 3h.

引用

页码：878 / 881

页数：4

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