Portal hypertension: pathophysiology, diagnosis and management

被引：69

作者：

Bloom, S. ^{[1
]}

Kemp, W. ^{[2
]}

Lubel, J. ^{[1
]}

机构：

[1] Eastern Hlth, Gastroenterol & Hepatol, Melbourne, Vic, Australia

[2] Alfred Hlth, Gastroenterol & Hepatol, Melbourne, Vic, Australia

来源：

INTERNAL MEDICINE JOURNAL | 2015年 / 45卷 / 01期

关键词：

portal hypertension; cirrhosis; varices; ascites; encephalopathy; SPONTANEOUS BACTERIAL PERITONITIS; GASTROESOPHAGEAL VARICES; HEPATORENAL-SYNDROME; CIRRHOTIC-PATIENTS; LIVER-DISEASE; BETA-BLOCKERS; THERAPY; METAANALYSIS; COAGULOPATHY; PROPHYLAXIS;

D O I：

10.1111/imj.12590

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Portal hypertension is an important complication of liver disease. As a result of elevated pressures within the portal vein several complications can arise, including the development of oesophageal and gastric varices, ascites, hepatic encephalopathy as well as complications secondary to circulatory dysfunction, such as hepatorenal syndrome, portopulmonary syndrome and hepatopulmonary syndrome. This review outlines the pathogenesis and diagnosis of portal hypertension and outlines the management of these various important clinical sequelae. The management of oesophageal and gastric varices is particularly important, and both the emergency management together with prophylactic management of this condition are described.

引用

页码：16 / 26

页数：11

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