The "hole" story of predatory outer-membrane vesicles

被引:15
|
作者
Clarke, Anthony J. [1 ]
机构
[1] Univ Guelph, Dept Mol & Cellular Biol, Guelph, ON N1G 2W1, Canada
关键词
membrane vesicles; outer-membrane vesicles; autolysins; predation; GRAM-NEGATIVE BACTERIA; POLYACRYLAMIDE-GEL ELECTROPHORESIS; PSEUDOMONAS-AERUGINOSA; ESCHERICHIA-COLI; BACILLUS-SUBTILIS; VIRULENCE FACTORS; LYTIC TRANSGLYCOSYLASES; EXTRACELLULAR VESICLES; HELICOBACTER-PYLORI; PROTEOMIC ANALYSIS;
D O I
10.1139/cjm-2017-0466
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
All Gram-negative bacteria release membrane vesicles. These vesicles contain a cargo of proteins and enzymes that include one or more autolysins. Autolysins are a group of enzymes with specificity for the different linkages within peptidoglycan sacculi that if uncontrolled cause bacteriolysis. This minireview, written in honor and memory of Terry Beveridge, presents an overview of autolytic activity and focuses on Beveridge's important original observations regarding predatory membrane vesicles and their associated autolysin cargo.
引用
收藏
页码:589 / 599
页数:11
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