Pt(II) complexes of 4-amino-4H-1,2,4-triazole

被引：8

作者：

Kavlakova, Maia ^{[1
]}

Bakalova, Adriana ^{[1
]}

Momekov, Georgi ^{[2
]}

Ivanov, Darvin ^{[1
]}

机构：

[1] Med Univ Sofia, Dept Chem, Fac Pharm, Dhaka 1000, Bangladesh

[2] Med Univ Sofia, Dept Pharmacol Pharmacotherapy & Toxicol, Fac Pharm, Dhaka 1000, Bangladesh

来源：

JOURNAL OF COORDINATION CHEMISTRY | 2010年 / 63卷 / 20期

关键词：

4-Amino-4H-1; 2; 4-triazole; Pt(II) complexes; Spectroscopic and structural elucidation; Cytotoxic activity; CANCER-CELL-LINES; DINUCLEAR PLATINUM(II) COMPLEXES; CRYSTAL-STRUCTURE; 1,2,4-TRIAZOLE COMPLEXES; CONTAINING PEPTIDES; ANTITUMOR-ACTIVITY; SPECTRAL-ANALYSIS; SOLID-STATE; CISPLATIN; AU(III)-COMPLEXES;

D O I：

10.1080/00958972.2010.516432

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The coordination ability of 4-amino-4H-1,2,4-triazole with Pt(II), both in solution and solid states, is elucidated by conventional and linear-polarized IR spectroscopy of oriented colloid suspensions in nematic host, 1H- and 13C-NMR, UV-Vis spectroscopy, mass spectrometry (ESI and FAB), TGV, and DSC methods. The interpretation of the spectroscopic characteristics of corresponding metal complexes is obtained by comparison with free 4-amino-4H-1,2,4-triazole. In addition, quantum chemical calculations of the last compound are performed to obtain data for electronic structures and optical properties of the ligand, thus supporting the experimental elucidation. The evaluation of the cell viability on a panel of human tumor cell lines is made. The new Pt(II) complexes exerted cytotoxic effects in a concentration-dependent manner.

引用

页码：3531 / 3540

页数：10

共 50 条

[1] New Mononuclear Cu(II) Complexes and 1D Chains with 4-Amino-4H-1,2,4-triazole
Dirtu, Marinela M.
Boland, Yves
Gillard, Damien
Tinant, Bernard
Robeyns, Koen
Safin, Damir A.
Devlin, Eamonn
Sanakis, Yiannis
Garcia, Yann
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2013, 14 (12): : 23597 - 23613
[2] A new cadmium coordination polymer based on 4-amino-4H-1,2,4-triazole
Saki, Maha
Boughzala, Habib
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2018, 74 : 147 - +
[3] Synthesis and Structures of Silver(I) Adducts with 4-Amino-4H-1,2,4-triazole
Wang, Qiao-Li
Xu, Hong
Hou, Hong-Wei
Yang, Guang
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2009, 64 (10): : 1143 - 1146
[4] Trinuclear Complexes of Nickel(II) and 4-Amino-1,2,4-triazole
Braeunlich, Irene
Medvedev, Michael
Dshemuchadse, Julia
Woerle, Michael
Caseri, Walter
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 2015, 641 (12-13): : 2344 - 2349
[5] Hexakis(μ2-4-amino-4H-1,2,4-triazole)hexachlorotricadmium(II)
Liu, XW
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2005, 61 : M1777 - M1778
[6] Synthesis and characterization of the copper(II) complexes with 3-amino-1,2,4-triazole, 4-amino-1,2,4-triazole and 3-amino-5-methylthio-1,2,4-triazole
Gabryszewski, M
POLISH JOURNAL OF CHEMISTRY, 1998, 72 (12) : 2519 - 2523
[7] RELEASE OF BENZOCAINE, PROCAINE, 2-AMINOTHIAZOLE AND 4-AMINO-4H-1,2,4-TRIAZOLE FROM POLYMER CARRIERS
KOLLI, M
MONTHEARD, JP
VERGNAUD, JM
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1992, 81 (2-3) : 103 - 110
[8] Nickel nanoflakes on 4-Amino-4H-1,2,4-triazole/graphene for sustainable hydrogen evolution in acid and alkaline media
Begum, Halima
Ahmed, Mohammad Shamsuddin
Kim, Young-Bae
APPLIED SURFACE SCIENCE, 2020, 515
[9] Studies on aromatase inhibitors .1. Synthesis and biological evaluation of 4-amino-4H-1,2,4-triazole derivatives
Okada, M
Yoden, T
Kawaminami, E
Shimada, Y
Kudoh, M
Isomura, Y
Shikama, H
Fujikura, T
CHEMICAL & PHARMACEUTICAL BULLETIN, 1996, 44 (10) : 1871 - 1879
[10] Syntheses and properties of the Co(II), Ni(II), Zn(II) and Cd(II) complexes with 3-amino-1,2,4-triazole, 4-amino-1,2,4-triazole, 3,5-diamino-1,2,4-triazole and 3-amino-5-methylthio-1,2,4-triazole
Gabryszewski, M
Wieczorek, B
POLISH JOURNAL OF CHEMISTRY, 1999, 73 (12) : 2061 - 2066

← 1 2 3 4 5 →