A lysosome-specific near-infrared fluorescent probe for in vitro cancer cell detection and non-invasive in vivo imaging

被引:15
|
作者
Mengji, Rakesh [1 ,2 ]
Acharya, Abchiranjit [1 ]
Vangala, Venugopal [1 ,2 ]
Jana, Avijit [1 ,2 ,3 ]
机构
[1] Indian Inst Chem Technol, Dept Appl Biol, CSIR, Hyderabad 500007, Andhra Pradesh, India
[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
[3] Indian Inst Chem Technol, CSIR, Dept Organ Synth & Proc Chem, Hyderabad 500007, Andhra Pradesh, India
关键词
ORGANIC NANOPARTICLES; GOLD NANORODS; EMISSION; DYES;
D O I
10.1039/c9cc07322a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Near-infrared (NIR) fluorescent probes have been developed as potential bio-materials having profound applications in diagnosis and clinical practice. Herein, we wish to disclose a highly photostable ultra-bright NIR probe for the specific detection of lysosomes in numerous cell lines. Furthermore, the applicability of the developed NIR probe was evaluated for in vivo imaging.
引用
收藏
页码:14182 / 14185
页数:4
相关论文
共 50 条
  • [21] A near-infrared biothiol-specific fluorescent probe for cancer cell recognition
    Liu, Li
    Lv, Rui-Jie
    Leung, Jong-Kai
    Zou, Qian
    Wang, Yue
    Li, Fei
    Liang, Wang
    Feng, Shun
    Wu, Ming-Yu
    ANALYST, 2019, 144 (16) : 4750 - 4756
  • [22] A novel ESIPT-ICT-based near-infrared fluorescent probe with large stokes-shift for the highly sensitive, specific, and non-invasive in vivo detection of cysteine
    Zhao, Lihe
    He, Xu
    Huang, Yibing
    Li, Jialiang
    Li, Yiling
    Tao, Shuo
    Sun, Ying
    Wang, Xinghua
    Ma, Pinyi
    Song, Daqian
    SENSORS AND ACTUATORS B-CHEMICAL, 2019, 296
  • [23] Lysosome-specific near-infrared fluorescent probe with large stokes shift for H2S imaging in U87 cells and brain glioma mice
    Li, Songjiao
    Liu, Ying
    Yang, Ting
    Deng, Min
    Cheng, Dan
    He, Longwei
    SENSORS AND ACTUATORS B-CHEMICAL, 2025, 426
  • [24] Initial results of in vivo non-invasive cancer imaging in the human breast using near-infrared photoacoustics
    Manohar, Srirang
    Vaartjes, Susanne E.
    van Hespen, Johan C. G.
    Klaase, Joost M.
    van den Engh, Frank M.
    Steenbergen, Wiendelt
    van Leeuwen, Ton G.
    OPTICS EXPRESS, 2007, 15 (19): : 12277 - 12285
  • [25] An activatable near-infrared fluorescent probe for tracking nitroxyl in vitro and in vivo
    Zhou, Zhe
    Xia, Xiaofeng
    Li, Zheng
    Zhou, Tianshuo
    Wang, Erfei
    Ma, Chao
    Lu, Cuifen
    Nie, Junqi
    Yang, Guichun
    Wang, Juan
    Fan, Guorun
    Ren, Jun
    Wang, Feiyi
    DYES AND PIGMENTS, 2023, 209
  • [26] A near-infrared, highly specific NQO1-activated turn-on fluorescent probe for the detection and imaging of cancer cells in vivo
    Punganuru, Surendra Reddy
    Arutla, Viswanath
    Srivenugopal, Kalkunte S.
    CANCER RESEARCH, 2019, 79 (13)
  • [27] A novel near-infrared ratiometric fluorescent probe targeting lysosomes for imaging HOCl in vitro and in vivo
    Chen, Xiong
    Jiang, Detao
    Jiang, Chen
    Yao, Cheng
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2023, 286
  • [28] A novel near-infrared fluorescent probe with a large Stokes shift for biothiol detection and application in in vitro and in vivo fluorescence imaging
    Liu, Keyin
    Shang, Huiming
    Kong, Xiuqi
    Lin, Weiying
    JOURNAL OF MATERIALS CHEMISTRY B, 2017, 5 (21) : 3836 - 3841
  • [29] Design of a ratiometric near-infrared fluorescent probe with double excitation for hydrazine detection in vitro and in vivo
    Zhang, Tengteng
    Lai, Youbo
    Lin, Weiying
    SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 837
  • [30] Novel near-infrared fluorescent probe for live cell imaging
    Wan, Meng
    Zhu, Yubing
    Zou, Jianjun
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2020, 19 (02) : 1213 - 1218