A lysosome-specific near-infrared fluorescent probe for in vitro cancer cell detection and non-invasive in vivo imaging

被引：15
|
作者：
Mengji, Rakesh [1 ,2 ]
Acharya, Abchiranjit [1 ]
Vangala, Venugopal [1 ,2 ]
Jana, Avijit [1 ,2 ,3 ]
机构：
[1] Indian Inst Chem Technol, Dept Appl Biol, CSIR, Hyderabad 500007, Andhra Pradesh, India
[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
[3] Indian Inst Chem Technol, CSIR, Dept Organ Synth & Proc Chem, Hyderabad 500007, Andhra Pradesh, India
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 94期
关键词：
ORGANIC NANOPARTICLES; GOLD NANORODS; EMISSION; DYES;
D O I：
10.1039/c9cc07322a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Near-infrared (NIR) fluorescent probes have been developed as potential bio-materials having profound applications in diagnosis and clinical practice. Herein, we wish to disclose a highly photostable ultra-bright NIR probe for the specific detection of lysosomes in numerous cell lines. Furthermore, the applicability of the developed NIR probe was evaluated for in vivo imaging.
引用
收藏
页码：14182 / 14185
页数：4
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