A Novel Representation Approach to DNA Sequence and Its Application

被引：10

作者：

Wang, Shi-Yuan ^{[1
,2
]}

Tian, Feng-Chun ^{[1
]}

Liu, Xiao ^{[1
]}

Wang, Jia ^{[1
]}

机构：

[1] Chongqing Univ, Coll Commun Engn, Chongqing 400044, Peoples R China

[2] Southwest Univ, Sch Elect & Informat Engn, Chongqing 400715, Peoples R China

来源：

IEEE SIGNAL PROCESSING LETTERS | 2009年 / 16卷 / 04期

关键词：

Biological information; DNA sequence; extended Kalman filter; gene prediction; symbolic dynamics; SYSTEMS;

D O I：

10.1109/LSP.2009.2014291

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The representation of a DNA sequence is the first stage of genome analysis. A wide variety of approaches has been proposed for different applications in bioinformatics. In this letter, based on the principle of symbolic dynamics, a novel representation approach is proposed, which maps DNA sequence into 3-D chaotic sequences of sawtooth function and completely conserve its biological information. With the application of the new representation approach to DNA sequence, three extended Kalman filters are used to implement gene prediction. Simulation results are presented to illustrate the validity and feasibility of the proposed representation approach to DNA sequence.

引用

页码：275 / 278

页数：4