EEG correlates of fatigue during administration of a neuropsychological test battery

被引:87
作者
Barwick, Fiona [1 ]
Arnett, Peter [1 ]
Slobounov, Semyon [2 ]
机构
[1] Penn State Univ, Dept Psychol, University Pk, PA 16802 USA
[2] Penn State Univ, Dept Kinesiol, University Pk, PA 16802 USA
关键词
Mental fatigue; EEG; Stroop Interference Test; EVENT-RELATED POTENTIALS; TRAUMATIC BRAIN-INJURY; SLEEP-DEPRIVATION; MULTIPLE-SCLEROSIS; DRIVER FATIGUE; WAKING EEG; PERFORMANCE; CONCUSSION; ALERTNESS; INDEXES;
D O I
10.1016/j.clinph.2011.06.027
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: Mental fatigue, a poorly understood symptom of sports-related concussion, ideally requires assessment across multiple modalities. Our study aimed to examine mental fatigue effects among 10 neurologically normal, athletically active students undergoing typical concussion testing. It is our intention to ultimately address the question whether fatigue effects due to mild traumatic brain injury (mTBI) may become confounded with fatigue effects due to testing effort. Methods: Fourteen athletically active and neurologically normal volunteers were initially recruited from Penn State University. Self-reported fatigue, neuropsychological performance, and electroencephalographic (EEG) activity were measured throughout the whole testing duration. EEG measures in frequency domain (e. g., relative power of theta, alpha, and beta bands) were examined over the course of neuropsychological (NP) test administration. Results: Predicted fatigue effects over the course of testing included: (a) increased self-reported fatigue; (b) increased errors on the Stroop Interference Test; (c) significantly increased relative power of theta activity during the Stroop Interference Test in frontal-central and parietal regions; and (d) migration of alpha activation from the occipital to anterior (left parietal and pre-central) regions during the Stroop Interference task administered at the beginning compared with the end of testing. Conclusions: Results supported predictions related to subjective fatigue and cognitive performance and offered partial support for predictions related to EEG activation patterns over the course of administering the NP testing. Significance: Neurologically intact and athletically active college students demonstrate effects related to fatigue after undergoing a typical sports concussion assessment battery, including an increase in subjectively experienced fatigue, a decrease in cognitive task performance accuracy and associated modulations in EEG activity. This finding should be considered by clinical practitioners while evaluating the symptoms of concussion and making a decision regarding the return-to-sport participation. (C) 2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:278 / 284
页数:7
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