A Three-Component Reaction to Construct β-Aminonitroso-α-Diazocarbonyl Compounds under Metal-Free Conditions

被引：7

作者：

Chen, Rongxiang ^{[1
]}

Lan, Jihong ^{[2
]}

Li, Feng ^{[1
]}

Wang, Kai-Kai ^{[1
]}

Xue, Yinghui ^{[1
]}

Xu, Canran ^{[1
]}

Liu, Lantao ^{[3
]}

机构：

[1] Xinxiang Univ, Sch Pharm, Xinxiang 453000, Henan, Peoples R China

[2] Xinxiang Univ, Sch Chem & Mat Engn, Xinxiang 453000, Henan, Peoples R China

[3] Shangqiu Normal Univ, Coll Chem & Chem Engn, Shangqiu 476000, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2022年 / 364卷 / 08期

基金：

中国国家自然科学基金;

关键词：

1,3,5-triazines; diazo compounds; tertbutyl nitrite; metal-free; three-component reaction; C-H FUNCTIONALIZATION; DIAZO; HEXAHYDRO-1,3,5-TRIAZINES; ARYL; AZIRIDINE-2-CARBOXYLATES; 1,3,5-TRIAZINES; SELECTIVITY; IODIDES; IMINES;

D O I：

10.1002/adsc.202200025

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A procedure for the transition-metal-free three-component reaction of 1,3,5-triazines, diazo compounds and tert-butyl nitrite has been described. This reaction goes through tandem nucleophilic attack to generate synthetically important beta-aminonitroso-alpha-diazocarbonyl compounds in moderate to good yields. This protocol is distinguished by the use of readily available starting materials, wide substrate scope and operational simplicity. Notably, a N-N bond and a C-C bond were formed simultaneously.

引用

页码：1422 / 1426

页数：5

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