Genomic imprinting beyond DNA methylation: a role for maternal histones

被引:29
作者
Hanna, Courtney W. [1 ,2 ]
Kelsey, Gavin [1 ,2 ]
机构
[1] Babraham Inst, Epigenet Programme, Cambridge CB22 3AT, England
[2] Univ Cambridge, Ctr Trophoblast Res, Cambridge CB2 3EG, England
基金
英国医学研究理事会; 英国生物技术与生命科学研究理事会;
关键词
PLACENTA; MAMMALS;
D O I
10.1186/s13059-017-1317-9
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Inheritance of DNA methylation states from gametes determines genomic imprinting in mammals. A new study shows that repressive chromatin in oocytes can also confer imprinting.
引用
收藏
页数:4
相关论文
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