State of the Art in Topical Wound-Healing Products

被引:40
作者
Fan, Kenneth [1 ]
Tang, Jennifer [1 ]
Escandon, Julia [1 ]
Kirsner, Robert S. [1 ]
机构
[1] Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA
关键词
DIABETIC FOOT ULCERS; VENOUS LEG ULCERS; GROWTH FACTOR-BB; SILVER SULFADIAZINE; HUMAN SKIN; POVIDONE-IODINE; EXTRACELLULAR-MATRIX; BACTERIAL COUNTS; ARTIFICIAL SKIN; SURGICAL WOUNDS;
D O I
10.1097/PRS.0b013e3181fbe275
中图分类号
R61 [外科手术学];
学科分类号
摘要
Chronic wounds represent a significant medical burden. Such wounds fail to normally progress through the stages of healing, often complicated by a proinflammatory milieu caused by increased proteinases, hypoxia, and bacterial burden. As a result, several modalities, such as dressings, antimicrobials, growth factors, and human skin substitutes, have been devised in an attempt to correct the chronic wound environment. This review addresses these modalities with a focus on evidence and randomized controlled trials. (Plast. Reconstr. Surg. 127 (Suppl.): 44S, 2011.)
引用
收藏
页码:44S / 59S
页数:16
相关论文
共 160 条
[1]   MOIST WOUND-HEALING UNDER A VAPOR PERMEABLE MEMBRANE [J].
ALPER, JC ;
WELCH, EA ;
GINSBERG, M ;
BOGAARS, H ;
MAGUIRE, P .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1983, 8 (03) :347-353
[2]   THE INVITRO RESPONSE OF FIBROBLASTS TO THE FLUID THAT ACCUMULATES UNDER A VAPOR-PERMEABLE MEMBRANE [J].
ALPER, JC ;
TIBBETTS, LL ;
SARAZEN, AA .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1985, 84 (06) :513-515
[3]  
*AM DIAB ASS, 1999, CONS DEV C DIAB FOOT
[4]  
Apelqvist J, 2000, DIABETES-METAB RES, V16, pS84, DOI 10.1002/1520-7560(200009/10)16:1+<::AID-DMRR113>3.0.CO
[5]  
2-S
[6]   Effect of silver on burn wound infection control and healing: Review of the literature [J].
Atiyeh, Bishara S. ;
Costagliola, Michel ;
Hayek, Shady N. ;
Dibo, Saad A. .
BURNS, 2007, 33 (02) :139-148
[8]   COMPARISON OF SYNTHETIC ADHESIVE MOISTURE VAPOR PERMEABLE AND FINE MESH GAUZE DRESSINGS FOR SPLIT-THICKNESS SKIN-GRAFT DONOR SITES [J].
BARNETT, A ;
BERKOWITZ, RL ;
MILLS, R ;
VISTNES, LM .
AMERICAN JOURNAL OF SURGERY, 1983, 145 (03) :379-381
[9]   Recent advances in wound healing [J].
Bello, YM ;
Phillips, TJ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (06) :716-718
[10]  
Bergin S, 2006, COCHRANE DB SYST REV, V1, DOI DOI 10.1002/14651858.CD005082.PUB2