Advances of nanomaterials-based strategies for fighting against COVID-19

被引:16
作者
Zeng, Chunxi [1 ]
Hou, Xucheng [1 ]
Bohmer, Margaret [2 ]
Dong, Yizhou [1 ,3 ,4 ,5 ,6 ,7 ]
机构
[1] Ohio State Univ, Coll Pharm, Div Pharmaceut & Pharmacol, 500 W 12Th Ave, Columbus, OH 43210 USA
[2] Ohio State Univ, Coll Med, Columbus, OH 43210 USA
[3] Ohio State Univ, Dept Biomed Engn, Columbus, OH 43210 USA
[4] Ohio State Univ, Ctr Clin & Translat Sci, Columbus, OH USA
[5] Ohio State Univ, Comprehens Canc Ctr, Columbus, OH 43210 USA
[6] Ohio State Univ, Dorothy M Davis Heart & Lung Res Inst, Columbus, OH 43210 USA
[7] Ohio State Univ, Dept Radiat Oncol, Columbus, OH 43210 USA
关键词
COVID-19; diagnostics; nanomaterials; SARS-CoV-2; therapeutics; vaccines; NANOPARTICLE VACCINES; DELIVERY; SARS-COV-2; NANOTECHNOLOGY; THERAPEUTICS; RESPONSES;
D O I
10.1002/VIW.20200180
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 100 million people globally due to its high infectivity. After decades of efforts on the studies of nanomaterials, researchers have applied nanomaterials-based strategies to combat the pandemic of the coronavirus disease 2019 (COVID-19). First, nanomaterials facilitate the development of easy, fast, and low-cost diagnostic assays to detect SARS-CoV-2 and related biomarkers. Second, nanomaterials enable the efficient delivery of viral antigens to antigen-presenting cells or serve as adjuvants in the host, leading to vaccine development at an unprecedented pace. Lastly, nanomaterials-based treatments may inhibit SARS-CoV-2 replication and reduce inflammation. Overall, nanomaterials have played important roles in controlling this COVID-19 pandemic. Here, we provide a brief overview of the representative examples of nanomaterials-based diagnostics, vaccines, and therapeutics in the fight against COVID-19.
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页数:15
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