Organocatalytic Asymmetric α-Functionalization of β-Ketoesters

被引：0

作者：

Fang Ling ^{[1
]}

Shi Yan ^{[1
]}

Zhu Chengjian ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, Nanjing 210093, Peoples R China

来源：

PROGRESS IN CHEMISTRY | 2010年 / 22卷 / 09期

关键词：

asymmetric synthesis; organocatalysis; beta-ketoesters; alpha-functionalization; CATALYTIC ENANTIOSELECTIVE FLUORINATION; DIASTEREOSELECTIVE MANNICH REACTIONS; KETO-ESTERS; CONJUGATE ADDITIONS; MICHAEL ADDITION; QUATERNARY STEREOCENTERS; 1,3-DICARBONYL COMPOUNDS; STEREOSELECTIVE-SYNTHESIS; TERTIARY STEREOCENTERS; ADJACENT QUATERNARY;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric organocatalysis has attracted a considerable amount attention for organic chemists. Due to the a-acidic hydrogen, beta-ketoesters could be functionalized in the presence of organic base or metal Lewis acid. Recent development of organocatalytic asymmetric alpha-functionalization of beta-ketoesters reactions is reviewed, and various electrophiles of these reactions are described.

引用

页码：1679 / 1686

页数：8

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