Non-sclerotic bone involvement in Erdheim-Chester: PET/CT and MRI findings in a 15-year-old boy

被引：10

作者：

White, Theresa V. ^{[1
]}

Silvester, Nicholas C. ^{[2
]}

Otero, Hansel J. ^{[3
]}

机构：

[1] Des Moines Univ, Mayfield Hts, OH USA

[2] Walter Reed Natl Mil Med Ctr, Bethesda, MD USA

[3] Childrens Natl Med Ctr, Dept Radiol, 111 Michigan Ave NW, Washington, DC 20010 USA

来源：

PEDIATRIC RADIOLOGY | 2016年 / 46卷 / 09期

关键词：

Adolescent; Brain; Erdheim-Chester disease; Histiocytosis; Magnetic resonance imaging; Non-Langerhans histiocytosis; Positron emission tomography; HISTIOCYTIC DISORDERS; DISEASE;

D O I：

10.1007/s00247-016-3594-y

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Erdheim-Chester disease is a rare form of non-Langerhans cell histiocytosis with multi-organ infiltration that occurs mainly in adults. Pediatric cases are extremely rare. Here we report a case of multisystemic Erdheim-Chester disease in a 15-year-old boy with central nervous system involvement and skeletal findings. Positron emission tomography (PET) and MRI were used to demonstrate characteristic bilateral, symmetrical medullary involvement of the metadiaphyses of long bones in the absence of the classic sclerotic radiographic appearance. This illustrates the potential for earlier diagnosis and visualization of therapeutic response in children.

引用

页码：1345 / 1349

页数：5

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