A novel strategy of nanotized herbal drugs and their delivery in the treatment of diabetes: Present status and future prospects

It is now recognised that one of the most far reaching developments in the management of diabetes (Diabetes mellitus) is the targeted delivery of herbal nanoparticles using nano-pumps, smart cells, nanorobots, and nanotized herbal drugs (NHDs). The design, development and targeted delivery of NHDs has now become a frontier research area. Previous research on nano-herbal medicines such as the methanolic extract of Triphala churn nanoparticle, Costus pictus D. Don (insulin plant) silver nanoparticles, and Talinum portulacifolium solid lipid nanoparticles indicated the possibility of overcoming the drawbacks of conventional management of glucose and controlling the complications of diabetes such as delayed wound healing and the side effects of synthetic drugs. Curcumin loaded poly (caprolactone) nanofibers were also found to have beneficial effects for treating diabetic ulcers; hence, the scientific data available to support the exploration of various nanotized herbal drugs or phyto-constituents which are effective in diabetes treatment and have wound healing capability. This paper focuses on the integration of nanotechnology with herbal remedies for the effective management of diabetes.