Derivation of the clinical grade human embryonic stem cell line RCe021-A (RC-17)

被引：13

作者：

De Sousa, P. A. ^{[1
,2
,3
]}

Tye, B. J. ^{[1
]}

Bruce, K. ^{[1
]}

Dand, P. ^{[1
]}

Russell, G. ^{[1
]}

Collins, D. M. ^{[1
]}

Greenshields, A. ^{[1
]}

McDonald, K. ^{[1
]}

Bradburn, H. ^{[1
]}

Allan, D. ^{[1
]}

Laurie, A. ^{[1
]}

Kunath, T.

Canham, M. A. ^{[3
]}

Downie, J. M. ^{[1
]}

Bateman, M. ^{[1
]}

Courtney, A. ^{[1
]}

机构：

[1] Roslin Cells Ltd, Nine Edinburgh Bioquarter, 9 Little France Rd, Edinburgh EH16 4UX, Midlothian, Scotland

[2] Univ Edinburgh, Ctr Clin Brain Sci, Chancellors Bldg,49 Little France Crescent, Edinburgh EH16 4SB, Midlothian, Scotland

[3] Univ Edinburgh, MRC Ctr Regenerat Med, Edinburgh EH8 9YL, Midlothian, Scotland

来源：

STEM CELL RESEARCH | 2016年 / 17卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/j.scr.2016.04.019

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

The human embryonic stem cell line RCe021-A (RC-17) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived from a day 3 embryo voluntarily donated as unsuitable or surplus to fertility requirements following informed consent. RCe021-A (RC17) shows normal pluripotency marker expression and differentiation to the three germ layers in vitro. It has a normal 46XX female karyotype and microsatellite PCR identity, HLA and blood group typing data are available. (C) 2016 The Authors. Published by Elsevier B.V.

引用

页码：1 / 5

页数：5

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