Studies on the synthesis of apoptolidin A. 2. Synthesis of the disaccharide unit

被引：18

作者：

Handa, Masaki ^{[1
]}

Smith, William J., III ^{[2
]}

Roush, William R. ^{[1
]}

机构：

[1] Scripps Florida, Dept Chem, Jupiter, FL 33458 USA

[2] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 73卷 / 03期

关键词：

D O I：

10.1021/jo7022526

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Disaccharide 3 correspoinding to the disaccharide unit of apoptolidin A. has been synthesized via the regio- and stereoselective TBS-OTf-promoted beta-glycosidation reaction of 2,6-dideoxy-2-iodo-beta-glucopyranosyl acetate (5) and p-methoxybenzyl 2,6-dideoxy-2-iodo-3-C-methyl-alpha-mannopyranoside (11).

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页码：1036 / 1039

页数：4

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