Histopathologic changes in liver and kidney tissues induced by carbaryl in Bufotes variabilis (Anura: Bufonidae)

被引：41

作者：

Cakici, Ozlem ^{[1
]}

机构：

[1] Ege Univ, Fac Sci, Dept Biol, Zool Sect, Izmir, Turkey

来源：

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY | 2015年 / 67卷 / 03期

关键词：

Carbaryl; Bujotes variabilis; Toad; Liver; Kidney; Histopathology; LEVANTINE FROG; EXPOSURE;

D O I：

10.1016/j.etp.2014.12.003

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The purpose of this work was to investigate for the first time histopathologic effects of carbaryl in liver and kidney tissues of Bufotes variabilis. After 96 h following exposure to carbaryl (low dose: 0.05, medium dose: 0.1 and high dose: 0.2 mg/g), the toads were euthanized and dissected. In liver tissue, vacuolization in hepatocytes, necrosis, mononuclear cell infiltration, an increase in melanomacrophage number, enlargement of sinusoids, hemorrhage and congestion were determined in exposed toads. In kidney tissue, mononuclear cell infiltration, hypertrophied Bowman's capsule cells, deformation, vacuolization, karyolysis and necrosis of renal tubule epithelium, brush border destruction, glomerular shrinkage, hemorrhage and fibrosis were observed in carbaryl-treated groups. According to this investigation, carbaryl caused histopathologic damages in liver and kidney tissues of B. variabilis. (C) 2014 Elsevier GmbH. All rights reserved.

引用

页码：237 / 243

页数：7

共 32 条

[1]

Aktar W, 2009, INTERDISCIPLINARY TO, V2, P1, DOI 10.2478/v10102-009-0001-7

[2] Axial-skeletal defects caused by Carbaryl in Xenopus laevis embryos [J].

Bacchetta, Renato ;

Mantecca, Paride ;

Andrioletti, Manuela ;

Vismara, Claudio ;

Vailati, Giouanni .

SCIENCE OF THE TOTAL ENVIRONMENT, 2008, 392 (01) :110-118

[3]

Basoglu M., 1994, Turkish Amphibians

[4] Specific time of exposure during tadpole development influences biological effects of the insecticide carbaryl in green frogs (Lithobates clamitans) [J].

Boone, Michelle D. ;

Hammond, S. Austin ;

Veldhoen, Nik ;

Youngquist, Melissa ;

Helbing, Caren C. .

AQUATIC TOXICOLOGY, 2013, 130 :139-148

[5] Carbaryl-induced Histopathologic Alterations in the Digestive Tract of the Levantine Frog, Pelophylax bedriagae (Anura: Ranidae) [J].

Cakici, Ozlem .

TOXICOLOGIC PATHOLOGY, 2014, 42 (06) :1032-1040

[6] Carbaryl-Induced Histopathologic Alterations on Testes of Levantine Frog, Pelophylax bedriagae (Anura: Ranidae) [J].

Cakici, Ozlem .

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2013, 91 (01) :96-101

[7] Acetylcholinesterase Inhibitors: Pharmacology and Toxicology [J].

Colovic, Mirjana B. ;

Krstic, Danijela Z. ;

Lazarevic-Pasti, Tamara D. ;

Bondzic, Aleksandra M. ;

Vasic, Vesna M. .

CURRENT NEUROPHARMACOLOGY, 2013, 11 (03) :315-335

[8] Declining downwind: Amphibian population declines in california and historical pesticide use [J].

Davidson, C .

ECOLOGICAL APPLICATIONS, 2004, 14 (06) :1892-1902

[9]

Delerue N, 2005, TRENDS IN EXPERIMENTAL HIGH ENERGY PHYSICS, P1

[10] Effects of aquatic exposure to the insecticide carbaryl are species-specific across life stages and mediated by heterospecific competitors in anurans [J].

Distel, Christopher A. ;

Boone, Michelle D. .

FUNCTIONAL ECOLOGY, 2010, 24 (06) :1342-1352

← 1 2 3 4 →