Comparison of two time-resolved detectors for diffuse optical tomography: photomultiplier tube-time-correlated single photon counting and multi-channel streak camera

被引:8
作者
Poulet, P [1 ]
Zint, CV [1 ]
Torregrossa, M [1 ]
Uhring, W [1 ]
Cunin, B [1 ]
机构
[1] ULP, UMR 7004 CNRS, Inst Biol Phys, F-67085 Strasbourg, France
来源
OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE V | 2003年 / 4955卷
关键词
diffuse optical tomography; time-resolved experiments; instrumentation; streak camera; time-correlated single photon counting;
D O I
10.1117/12.476841
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Two experimental setups for time-resolved diffuse optical tomography (DOT) are described. The first involves a titanium-sapphire laser and a streak camera in a synchroscan mode. A multiple-arm light guide allows to measure simultaneously the temporal profiles of photons re-emitted at different boundary sites of the objects studied. The second one uses picosecond laser diodes and a multiple-anode micro-channel plate photomultiplier tube followed by parallel time-correlated single photon counting channels. The two instruments are described and their main specifications compared: instrument response and time resolution, sweep time, temporal stability, sensitivity and its inter-channel variation, cross-talk between adjacent channels. We will also discuss detector-specific data analysis prior to image reconstruction. Both instruments have been tested with phantoms simulating tissues and the absorption and reduced scattering images obtained have been compared.
引用
收藏
页码:154 / 163
页数:10
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