The termination of PI3K signalling by SHIP1 and SHIP2 inositol 5-phosphatases

被引:74
|
作者
Backers, K [1 ]
Blero, D [1 ]
Paternotte, N [1 ]
Zhang, J [1 ]
Erneux, C [1 ]
机构
[1] Free Univ Brussels, Interdisciplinary Res Inst IRIBHM, B-1070 Brussels, Belgium
来源
ADVANCES IN ENZYME REGULATION, VOL 43 | 2003年 / 43卷
关键词
D O I
10.1016/S0065-2571(02)00043-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:15 / 28
页数:14
相关论文
共 50 条
  • [1] The two SH2-domain-containing inositol 5-phosphatases SHIP1 and SHIP2 are coexpressed in human T lymphocytes
    Bruyns, C
    Pesesse, X
    Moreau, C
    Blero, D
    Erneux, C
    BIOLOGICAL CHEMISTRY, 1999, 380 (7-8) : 969 - 974
  • [2] Molecular basis of the recruitment of the SH2 domain-containing inositol 5-phosphatases SHIP1 and SHIP2 by FcγRIIB
    Bruhns, P
    Vély, F
    Malbec, O
    Fridman, WH
    Vivier, E
    Daëron, M
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (48) : 37357 - 37364
  • [3] The Functional Roles of the Src Homology 2 Domain-Containing Inositol 5-Phosphatases SHIP1 and SHIP2 in the Pathogenesis of Human Diseases
    Mueller, Spike Murphy
    Juecker, Manfred
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (10)
  • [4] The SH2 Domains of Inositol Polyphosphate 5-Phosphatases SHIP1 and SHIP2 Have Similar Ligand Specificity but Different Binding Kinetics
    Zhang, Yanyan
    Wavreille, Anne-Sophie
    Kunys, Andrew R.
    Pei, Dehua
    BIOCHEMISTRY, 2009, 48 (46) : 11075 - 11083
  • [5] Targeting SHIP1 and SHIP2 in Cancer
    Pedicone, Chiara
    Meyer, Shea T.
    Chisholm, John D.
    Kerr, William G.
    CANCERS, 2021, 13 (04) : 1 - 24
  • [6] Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2
    Bradshaw, William J.
    Kennedy, Emma C.
    Moreira, Tiago
    Smith, Luke A.
    Chalk, Rod
    Katis, Vittorio L.
    Benesch, Justin L. P.
    Brennan, Paul E.
    Murphy, Emma J.
    Gileadi, Opher
    STRUCTURE, 2024, 32 (04) : 453 - 466.e6
  • [7] Small molecule targeting of SHIP1 and SHIP2
    Kerr, William G.
    Pedicone, Chiara
    Dormann, Shawn
    Pacherille, Angela
    Chisholm, John D.
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2020, 48 (01) : 291 - 300
  • [8] Therapeutic Potential of SH2 Domain-Containing Inositol-5′-Phosphatase 1 (SHIP1) and SHIP2 Inhibition in Cancer
    Gwenny M. Fuhler
    Robert Brooks
    Bonnie Toms
    Sonia Iyer
    Elizabeth A. Gengo
    Mi-Young Park
    Matthew Gumbleton
    Dennis R. Viernes
    John D. Chisholm
    William G. Kerr
    Molecular Medicine, 2012, 18 : 65 - 75
  • [9] Therapeutic Potential of SH2 Domain-Containing Inositol-5′-Phosphatase 1 (SHIP1) and SHIP2 Inhibition in Cancer
    Fuhler, Gwenny M.
    Brooks, Robert
    Toms, Bonnie
    Iyer, Sonia
    Gengo, Elizabeth A.
    Park, Mi-Young
    Gumbleton, Matthew
    Viernes, Dennis R.
    Chisholm, John D.
    Kerr, William G.
    MOLECULAR MEDICINE, 2012, 18 (01) : 65 - 75
  • [10] The SHIP2/PI3K pathway plays a pivotal role in modulating energy balance
    Gowen, L
    Wortley, KE
    Okomoto, H
    Liu, R
    Malinova, L
    Wiegand, SJ
    Sleeman, MW
    DIABETES, 2005, 54 : A384 - A384