Acid Resistance Contributes to the High-Pressure Carbon Dioxide Resistance of Escherichia coli K-12

被引:5
|
作者
Furukawa, Soichi [1 ]
Shimazaki, Junji [1 ]
Kawaharada, Kazumichi [1 ]
Matsuda, Tsukasa [1 ]
Aoyagi, Hiroki [1 ]
Wakabayashi, Hidekazu [1 ]
Ogihara, Hirokazu [1 ]
Yamasaki, Makari [1 ]
Morinaga, Yasushi [1 ]
机构
[1] Nihon Univ, Coll Bioresource Sci, Dept Food Biosci & Biotechnol, Fujisawa, Kanagawa 2528510, Japan
关键词
GEOBACILLUS-STEAROTHERMOPHILUS SPORES; STRESS-RESPONSE; INACTIVATION; TRANSCRIPTION; DKSA; MICROORGANISMS; DECARBOXYLASE; TOLERANCE; PPGPP;
D O I
10.1007/s00284-014-0674-9
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Effect of deletion of acid resistant genes of E. coli on the high-pressure carbon dioxide (HPC) resistance was investigated. Genes coding amino acid decarboxylases, such as lysine, arginine, and glutamate decarboxylase, were found to contribute to HPC resistance. Protonophore-treated cells showed hypersensitivity to HPC, confirming that HPC induced cytoplasm acidification and exerted severe damage on cells by intrusion of gaseous carbon dioxide into cytoplasm.
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页码:1 / 5
页数:5
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