The Level of Cortical Afferent Inhibition in Acute Stroke Correlates With Long-Term Functional Recovery in Humans

被引：42

作者：

Di Lazzaro, Vincenzo ^{[1
,2
]}

Profice, Paolo ^{[1
]}

Pilato, Fabio ^{[1
]}

Capone, Fioravante ^{[1
]}

Ranieri, Federico ^{[1
]}

Florio, Lucia ^{[1
]}

Colosimo, Cesare ^{[3
]}

Pravata, Emanuele ^{[3
]}

Pasqualetti, Patrizio ^{[2
]}

Dileone, Michele ^{[1
]}

机构：

[1] Univ Cattolica, Ist Neurol, I-00168 Rome, Italy

[2] San Giovanni Calibita Fatebenefratelli Hosp, Dept Neurosci, AFaR Fatebenefratelli, Rome, Italy

[3] Univ Cattolica, Inst Radiol, I-00168 Rome, Italy

来源：

STROKE | 2012年 / 43卷 / 01期

关键词：

GABA; transcranial magnetic stimulation; TRANSCRANIAL MAGNETIC STIMULATION; MOTOR CORTEX; BRAIN;

D O I：

10.1161/STROKEAHA.111.631085

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background and Purpose-Using transcranial magnetic stimulation, we investigated short-interval intracortical inhibition and short-latency afferent inhibition in acute ischemic stroke. Methods-We evaluated short-interval intracortical inhibition and short-latency afferent inhibition in the affected hemisphere and unaffected hemisphere in 16 patients and correlated electrophysiological parameters with outcome at 6 months. Results-Affected hemisphere short-latency afferent inhibition was significantly reduced in patients, and short-latency afferent inhibition level correlated with functional outcome. Conclusions-Reduced afferent inhibition in acute stroke correlates with long-term recovery. (Stroke. 2012;43:250-252.)

引用

收藏

页码：250 / U493

页数：10

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