Risk of cancer in patients following chronic dialysis and kidney graft

被引:7
作者
Janus, Nicolas [1 ]
Launay-Vacher, Vincent [1 ]
Ferrero, Jean-Marc [2 ]
Thariat, Juliette [3 ]
机构
[1] Hop La Pitie Salpetriere, Serv ICAR, Serv Nephrol, F-75013 Paris, France
[2] Ctr Antoine Lacassagne, Med Oncol Serv, F-06200 Nice, France
[3] Ctr Antoine Lacassagne, Serv Radiotherapie Oncol, F-06200 Nice, France
关键词
risk; cancer; transplantation; kidney graft; dialysis; RENAL-TRANSPLANT RECIPIENTS; URINARY-TRACT; SKIN CANCERS; DISEASE; GROWTH; INSUFFICIENCY; MALIGNANCIES; MORTALITY; RAPAMYCIN; VACCINES;
D O I
10.1684/bdc.2012.1545
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background. A high prevalence of renal insufficiency has been observed in cancer patients as well as a high incidence of de novo cancer in dialysis or renal transplant patients. Material and methods. We aimed to determine the incidence of cancer in patients under dialysis and in kidney transplant recipients through a search of the literature. Results. Under chronic dialysis, the risk of cancer increases from 1.1 to 1.8 in comparison to the general population. These risks reach 2.5 to 3.9 in renal transplant patients, but depend on the type of tumor. Conclusion. In transplant recipients, the risk of cancer induced by immunosuppressive therapy requires a specific follow-up and a screening for any medical history of cancer in the donor and the recipient. triangle
引用
收藏
页码:285 / 293
页数:9
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