Adaptive designs for clinical trials have potential advantages, but statistical challenges lurk! COMMENT

被引:2
作者
Lo, S. N. [1 ,2 ]
Thompson, J. F. [1 ,2 ]
机构
[1] Univ Sydney, Melanoma Inst Australia, Sydney, NSW, Australia
[2] Univ Sydney, Fac Med & Hlth, Sydney, NSW, Australia
基金
英国医学研究理事会;
关键词
D O I
10.1111/bjd.20828
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:205 / 206
页数:2
相关论文
共 50 条
[31]   Adaptive designs for clinical trials with highly successful treatments [J].
Ivanova, A ;
Rosenberger, WF .
DRUG INFORMATION JOURNAL, 2001, 35 (04) :1087-1093
[32]   Efficiency Perspectives on Adaptive Designs in Stroke Clinical Trials [J].
Cheung, Ken ;
Kaufmann, Petra .
STROKE, 2011, 42 (10) :2990-U502
[33]   Perspectives on the Use of Adaptive Designs in Clinical Trials. Part I. Statistical Considerations and Issues [J].
Wang, Sue-Jane .
JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2010, 20 (06) :1090-1097
[34]   On statistical analysis for placebo-challenging designs in clinical trials [J].
Chow, SC ;
Shao, J ;
Ho, HT .
STATISTICS IN MEDICINE, 2000, 19 (08) :1029-1037
[35]   Benefits, challenges and obstacles of adaptive clinical trial designs [J].
Shein-Chung Chow ;
Ralph Corey .
Orphanet Journal of Rare Diseases, 6
[36]   Benefits, challenges and obstacles of adaptive clinical trial designs [J].
Chow, Shein-Chung ;
Corey, Ralph .
ORPHANET JOURNAL OF RARE DISEASES, 2011, 6
[37]   Adaptive designs undertaken in clinical research: a review of registered clinical trials [J].
Isabella Hatfield ;
Annabel Allison ;
Laura Flight ;
Steven A. Julious ;
Munyaradzi Dimairo .
Trials, 17
[38]   Adaptive designs undertaken in clinical research: a review of registered clinical trials [J].
Hatfield, Isabella ;
Allison, Annabel ;
Flight, Laura ;
Julious, Steven A. ;
Dimairo, Munyaradzi .
TRIALS, 2016, 17
[39]   Clinical Trials in FSGS: Past Challenges and New Trial Designs [J].
Gipson, Deb .
SEMINARS IN NEPHROLOGY, 2016, 36 (06) :453-459
[40]   Balancing statistical and ethical considerations in planning clinical trials: recommendations for response-adaptive randomization urn designs [J].
Piccorelli, Annalisa V. ;
Fraker, Sarah A. .
JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2018, 28 (06) :1105-1118