Sex Differences in the Treatment of HIV

被引:13
作者
Cohn, Jennifer [1 ]
Ake, Julie [2 ]
Moorhouse, Michelle [3 ]
Godfrey, Catherine [4 ]
机构
[1] Grand Saconnex, Route Morillons, Geneva, Switzerland
[2] Walter Reed Army Inst Res, Robert Grant Ave, Silver Spring, MD 20910 USA
[3] Univ Witwatersrand, Johannesburg, South Africa
[4] Off Global AIDS Coordinator, Washington, DC 20003 USA
关键词
HIV; Women; Sex differences; LMIC; ANTIRETROVIRAL THERAPY; INFECTED WOMEN; MONOCYTE ACTIVATION; HEART-DISEASE; SOUTH-AFRICA; CARDIOVASCULAR-DISEASE; MYOCARDIAL-INFARCTION; TREATMENT PROGRAMS; PREDICT MORTALITY; IMMUNE ACTIVATION;
D O I
10.1007/s11904-020-00499-x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Purpose of Review Biological and societal influences are different for men and women leading to different HIV outcomes and related infectious and non-infectious complications. This review evaluates sex differences in the epidemiology and immunological response to HIV and looks at major complications and coinfections, as well as care delivery systems focusing on low- and middle-income countries (LMICs) where most people with HIV live. Recent Findings More women than men access testing and treatment services in LMIC; women are more likely to be virologically suppressed in that environment. There is a growing recognition that the enhanced immunological response to several pathogens including HIV may result in improved outcomes for infectious comorbidities but may result in a greater burden of non-communicable diseases. Men and women have different requirements for HIV care. Attention to these differences may improve outcomes for all.
引用
收藏
页码:373 / 384
页数:12
相关论文
共 133 条
  • [1] Conceptualizing the Risks of Coronary Heart Disease and Heart Failure Among People Aging with HIV: Sex-Specific Considerations
    Abelman R.A.
    Mugo B.M.
    Zanni M.V.
    [J]. Current Treatment Options in Cardiovascular Medicine, 2019, 21 (8)
  • [2] Short-term weight gain after antiretroviral therapy initiation and subsequent risk of cardiovascular disease and diabetes: the D:A:D study
    Achhra, A. C.
    Mocroft, A.
    Reiss, P.
    Sabin, C.
    Ryom, L.
    de Wit, S.
    Smith, C. J.
    Monforte, A. d'Arminio
    Phillips, A.
    Weber, R.
    Lundgren, J.
    Law, M. G.
    [J]. HIV MEDICINE, 2016, 17 (04) : 255 - 268
  • [3] Sex-Based Differences in HIV Type 1 Pathogenesis
    Addo, Marylyn M.
    Altfeld, Marcus
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2014, 209 : S86 - S92
  • [4] Differentiated service delivery: a qualitative study of people living with HIV and accessing care in a tertiary facility in Ghana
    Adjetey, Vincent
    Obiri-Yeboah, Dorcas
    Dornoo, Bernard
    [J]. BMC HEALTH SERVICES RESEARCH, 2019, 19 (1)
  • [5] Noninfectious Comorbidity in the African Cohort Study
    Ake, Julie A.
    Polyak, Christina S.
    Crowell, Trevor A.
    Kiweewa, Francis
    Semwogerere, Michael
    Maganga, Lucas
    Bahemana, Emmanuel
    Maswai, Jonah
    Langat, Rither
    Owuoth, John
    Otieno, Solomon
    Keshinro, Babajide
    Esber, Allahna L.
    Liu, Michelle
    Eller, Leigh Anne
    Ganesan, Kavitha
    Parikh, Ajay P.
    Hamm, Tiffany E.
    Robb, Merlin L.
    Hickey, Patrick W.
    Valcour, Victor G.
    Michael, Nelson L.
    Falodun, O.
    Song, K.
    Milazzo, M.
    Zhang, C.
    Deshano, R.
    Thompson, C.
    Smith, G.
    Mebrahtu, T.
    Coakley, P.
    Lombardi, K.
    Imbach, M.
    Peel, S.
    Malia, J.
    Kroidl, A.
    Kroidl, I.
    Geldmacher, C.
    Kafeero, C.
    Nambuya, A.
    Tegamanyi, J.
    Birungi, H.
    Mugagga, O.
    Nassali, G.
    Wangiri, P.
    Nantabo, M.
    Nambulondo, P.
    Atwijuka, B.
    Asiimwe, A.
    Nabanoba, C. T.
    [J]. CLINICAL INFECTIOUS DISEASES, 2019, 69 (04) : 639 - 647
  • [6] Anastos K, 2000, J ACQ IMMUN DEF SYND, V24, P218
  • [7] [Anonymous], 2011, PROGR REP 2011 GLOB
  • [8] [Anonymous], 2007, CLASS ANTIRETROVIRAL, V356, P1723, DOI [10.1056/NEJMoa062744, DOI 10.1056/NEJM0A062744]
  • [9] Using a composite adherence tool to assess ART response and risk factors of poor adherence in pregnant and breastfeeding HIV-positive Cameroonian women at 6 and 12 months after initiating option B
    Atanga, Pascal N.
    Ndetan, Harrison T.
    Fon, Peter N.
    Meriki, Henry D.
    Muffih, Tih P.
    Achidi, Eric A.
    Hoelscher, Michael
    Kroidl, Arne
    [J]. BMC PREGNANCY AND CHILDBIRTH, 2018, 18
  • [10] A Decade of Antiretroviral Therapy Scale-up in Mozambique: Evaluation of Outcome Trends and New Models of Service Delivery Among More Than 300,000 Patients Enrolled During 2004-2013
    Auld, Andrew F.
    Shiraishi, Ray W.
    Couto, Aleny
    Mbofana, Francisco
    Colborn, Kathryn
    Alfredo, Charity
    Ellerbrock, Tedd V.
    Xavier, Carla
    Jobarteh, Kebba
    [J]. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2016, 73 (02) : E11 - E22