Bioactive Gyroid Scaffolds Formed by Sacrificial Templating of Nanocellulose and Nanochitin Hydrogels as Instructive Platforms for Biomimetic Tissue Engineering

被引：195

作者：

Torres-Rendon, Jose Guillermo ^{[1
]}

Femmer, Tim ^{[1
,2
]}

De Laporte, Laura ^{[1
]}

Tigges, Thomas ^{[1
]}

Rahimi, Khosrow ^{[1
]}

Gremse, Felix ^{[3
]}

Zafarnia, Sara ^{[3
]}

Lederle, Wiltrud ^{[3
]}

Ifuku, Shinsuke ^{[4
]}

Wessling, Matthias ^{[1
,2
]}

Hardy, John G. ^{[5
]}

Walther, Andreas ^{[1
]}

机构：

[1] DWI Leibniz Inst Interact Mat, D-52056 Aachen, Germany

[2] Rhein Westfal TH Aachen, Chem Proc Engn AVT CVT, D-52064 Aachen, Germany

[3] Rhein Westfal TH Aachen, Fac Med, Dept Expt Mol Imaging, D-52074 Aachen, Germany

[4] Tottori Univ, Grad Sch Engn, Tottori 6808502, Japan

[5] Queens Univ Belfast, Ctr Med Biol, Sch Pharm, Belfast BT9 7BL, Antrim, North Ireland

来源：

ADVANCED MATERIALS | 2015年 / 27卷 / 19期

关键词：

3D printing; cellulose nanofibrils; chitin nanofibrils; hydrogel scaffolds; stem cells; NANOFIBRILLAR CELLULOSE HYDROGEL; CHITIN NANOFIBERS; IN-VITRO; NATIVE CELLULOSE; ELASTIC-MODULUS; ALPHA-CHITIN; CELL-CULTURE; REGENERATIVE MEDICINE; MECHANICAL-PROPERTIES; CRYSTALLINE REGIONS;

D O I：

10.1002/adma.201405873

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A sacrificial templating process using lithographically printed minimal surface structures allows complex de novo geometries of delicate hydrogel materials. The hydrogel scaffolds based on cellulose and chitin nanofibrils show differences in terms of attachment of human mesenchymal stem cells, and allow their differentiation into osteogenic outcomes. The approach here serves as a first example toward designer hydrogel scaffolds viable for biomimetic tissue engineering. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2989 / 2995

页数：7

共 72 条

[1] Tunable Colors in Opals and Inverse Opal Photonic Crystals [J].

Aguirre, Carlos I. ;

Reguera, Edilso ;

Stein, Andreas .

ADVANCED FUNCTIONAL MATERIALS, 2010, 20 (16) :2565-2578

[2] 25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine [J].

Annabi, Nasim ;

Tamayol, Ali ;

Uquillas, Jorge Alfredo ;

Akbari, Mohsen ;

Bertassoni, Luiz E. ;

Cha, Chaenyung ;

Camci-Unal, Gulden ;

Dokmeci, Mehmet R. ;

Peppas, Nicholas A. ;

Khademhosseini, Ali .

ADVANCED MATERIALS, 2014, 26 (01) :85-124

[3] Engineering microporosity in bacterial cellulose scaffolds [J].

Backdahl, Henrik ;

Esguerra, Maricris ;

Delbro, Dick ;

Risberg, Bo ;

Gatenholm, Paul .

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2008, 2 (06) :320-330

[4] Humidity and Multiscale Structure Govern Mechanical Properties and Deformation Modes in Films of Native Cellulose Nanofibrils [J].

Benitez, Alejandro J. ;

Torres-Rendon, Jose ;

Poutanen, Mikko ;

Walther, Andreas .

BIOMACROMOLECULES, 2013, 14 (12) :4497-4506

[5] Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture [J].

Bhattacharya, Madhushree ;

Malinen, Melina M. ;

Lauren, Patrick ;

Lou, Yan-Ru ;

Kuisma, Saara W. ;

Kanninen, Liisa ;

Lille, Martina ;

Corlu, Anne ;

GuGuen-Guillouzo, Christiane ;

Ikkala, Olli ;

Laukkanen, Antti ;

Urtti, Arto ;

Yliperttula, Marjo .

JOURNAL OF CONTROLLED RELEASE, 2012, 164 (03) :291-298

[6] Aerogel Microspheres from Natural Cellulose Nanofibrils and Their Application as Cell Culture Scaffold [J].

Cai, Hongli ;

Sharma, Sudhir ;

Liu, Wenying ;

Mu, Wei ;

Liu, Wei ;

Zhang, Xiaodan ;

Deng, Yulin .

BIOMACROMOLECULES, 2014, 15 (07) :2540-2547

[7] Advances in assessment of bone porosity, permeability and interstitial fluid flow [J].

Cardoso, Luis ;

Fritton, Susannah P. ;

Gailani, Gaffar ;

Benalla, Mohammed ;

Cowin, Stephen C. .

JOURNAL OF BIOMECHANICS, 2013, 46 (02) :253-265

[8] Influence of the degree of acetylation on some biological properties of chitosan films [J].

Chatelet, C ;

Damour, O ;

Domard, A .

BIOMATERIALS, 2001, 22 (03) :261-268

[9] Chitosan-Based Inverse Opals: Three-Dimensional Scaffolds with Uniform Pore Structures for Cell Culture [J].

Choi, Sung-Wook ;

Xie, Jingwei ;

Xia, Younan .

ADVANCED MATERIALS, 2009, 21 (29) :2997-+

[10] BIOCOMPATIBILITY OF POTENTIAL WOUND MANAGEMENT PRODUCTS - FUNGAL MYCELIA AS A SOURCE OF CHITIN/CHITOSAN AND THEIR EFFECT ON THE PROLIFERATION OF HUMAN F1000 FIBROBLASTS IN CULTURE [J].

CHUNG, LY ;

SCHMIDT, RJ ;

HAMLYN, PF ;

SAGAR, BF ;

ANDREWS, AM ;

TURNER, TD .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1994, 28 (04) :463-469

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