Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents

被引：103

作者：

Concepcion Serrano, M. ^{[1
]}

Gutierrez, Maria C. ^{[1
]}

Jimenez, Ricardo ^{[1
]}

Luisa Ferrer, M. ^{[1
]}

del Monte, Francisco ^{[1
]}

机构：

[1] CSIC, ICMM, E-28049 Madrid, Spain

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 04期

关键词：

BIODEGRADABLE ELASTOMERS; IONIC LIQUIDS; STRATEGY; DRUG;

D O I：

10.1039/c1cc15284j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Poly(octanediol-co-citrate) elastomers containing high loading of lidocaine were synthesized at temperatures below 100 degrees C by means of using deep eutectic mixtures of 1,8-octanediol and lidocaine. The preservation of lidocaine integrity resulted in high-capacity drug-eluting elastomers.

引用

收藏

页码：579 / 581

页数：3

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