Hepatocellular carcinoma treated with radio frequency ablation: An early evaluation with magnetic resonance imaging

被引:24
作者
Khankan, Azzam A. [2 ]
Murakami, Takamichi [1 ]
Onishi, Hiromitsu [3 ]
Matsushita, Masaki [4 ]
Iannaccone, Riccardo [5 ]
Aoki, Yoshiko [4 ]
Tono, Takeshi [6 ]
Kim, Tonsok [3 ]
Hori, Masatoshi [3 ]
Osuga, Keigo [3 ]
Passariello, Roberto [5 ]
Nakamura, Hironobu [3 ]
机构
[1] Kinki Univ, Sch Med, Dept Radiol, Osaka 5898511, Japan
[2] Damascus Univ Hosp, Dept Radiol, Damascus, Syria
[3] Osaka Univ, Grad Sch Med, Dept Radiol, Osaka, Japan
[4] NTT W Hosp, Dept Radiol, Osaka, Japan
[5] Univ Roma La Sapienza, Dept Radiol Sci, Rome, Italy
[6] NTT W Hosp, Dept Surg, Osaka, Japan
关键词
magnetic resonance imaging (MRI); liver neoplasms; radio frequency ablation (RFA); hepatocellular carcinoma (HCC); computed tomography (CT); therapy evaluation;
D O I
10.1002/jmri.21050
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: To determine the usefulness of nonenhanced T1-weighted spoiled gradient-recalled acquisition in the steady-state (SPGR) MRI in the early assessment of the efficacy of radio frequency (RF) therapy for hepatocellular carcinoma (HCC). Materials and Methods: A total of 23 patients with 28 HCC nodules treated with percutaneous RF ablation underwent nonenhanced MRI within two days after the RF procedure and contrast-enhanced computed tomography (CT) one week after. MR assessment of ablation efficacy according to the concentric zonal pattern on T1-weighted SPGR imaging was compared with the one-week CT and presence of local recurrence by means of follow-up study for 12 months or more. Results: In 18 of 28 ablated nodules, SPGR images revealed a central hyperintense zone covering the entire tumor, CT showed a nonenhanced area covering the entire tumor, and no local recurrence was demonstrated in the follow-up studies. In nine of 28 nodules, the central hyperintense zone did not cover the entire tumor; and local recurrence was demonstrated in three nodules. In the remaining one nodule, no signal change was seen in the treated area on SPGR images and CT showed the presence of residual viable tumor. Conclusion: Nonenhanced T1-weighted MRI was considered useful for early assessment of the efficacy of RF therapy for HCC.
引用
收藏
页码:546 / 551
页数:6
相关论文
共 26 条
[1]   TREATMENT OF HEPATOCELLULAR-CARCINOMA WITH PERCUTANEOUS ETHANOL INJECTION - EVALUATION WITH CONTRAST-ENHANCED MR-IMAGING [J].
BARTOLOZZI, C ;
LENCIONI, R ;
CARAMELLA, D ;
MAZZEO, S ;
CIANCIA, EM .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1994, 162 (04) :827-831
[2]   Surgical margin in hepatic resection for colorectal metastasis - A critical and improvable determinant of outcome [J].
Cady, B ;
Jenkins, RL ;
Steele, GD ;
Lewis, WD ;
Stone, MD ;
McDermott, WV ;
Jessup, JM ;
Bothe, A ;
Lalor, P ;
Lovett, EJ ;
Lavin, P ;
Linehan, DC .
ANNALS OF SURGERY, 1998, 227 (04) :566-571
[3]  
CHOI TK, 1990, HEPATO-GASTROENTEROL, V37, P172
[4]   Minimally invasive treatment of malignant hepatic tumors: At the threshold of a major breakthrough [J].
Dodd, GD ;
Soulen, MC ;
Kane, RA ;
Livraghi, T ;
Lees, WR ;
Yamashita, Y ;
Gillams, AR ;
Karahan, OI ;
Rhim, H .
RADIOGRAPHICS, 2000, 20 (01) :9-27
[5]   Hepatic tumors treated with percutaneous radio-frequency ablation: CT and MR imaging follow-up [J].
Dromain, C ;
de Baere, T ;
Elias, D ;
Kuoch, V ;
Ducreux, M ;
Boige, V ;
Petrow, P ;
Roche, A ;
Sigal, R .
RADIOLOGY, 2002, 223 (01) :255-262
[6]   Tumor ablation with radio-frequency energy [J].
Gazelle, GS ;
Goldberg, SN ;
Solbiati, L ;
Livraghi, T .
RADIOLOGY, 2000, 217 (03) :633-646
[7]   Thermal ablation therapy for focal malignancy: A unified approach to underlying principles, techniques, and diagnostic imaging guidance [J].
Goldberg, SN ;
Gazelle, GS ;
Mueller, PR .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2000, 174 (02) :323-331
[8]   MR imaging-histopathologic correlation of radiofrequency thermal ablation lesion in a rabbit liver model: Observation during acute and chronic stages [J].
Lee, JD ;
Lee, JM ;
Kim, SW ;
Kim, CS ;
Mun, WS .
KOREAN JOURNAL OF RADIOLOGY, 2001, 2 (03) :151-158
[9]   RESPONSE OF HEPATOCELLULAR-CARCINOMA TO PERCUTANEOUS ETHANOL INJECTION - CT AND MR EVALUATION [J].
LENCIONI, R ;
CARAMELLA, D ;
BARTOLOZZI, C .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1993, 17 (05) :723-729
[10]   Hepatocellular carcinoma: evaluation of therapeutic response to interventional procedures [J].
Lim, HK ;
Han, JK .
ABDOMINAL IMAGING, 2002, 27 (02) :168-179