No Evidence of Dengue Virus Infections in Several Species of Bats Captured in Central and Southern Mexico

被引:15
作者
Cabrera-Romo, S. [1 ]
Ramirez, C. Max [2 ]
Recio-Totoro, B. [3 ]
Tolentino-Chi, J. [4 ]
Lanz, H. [3 ]
del Angel, R. M. [1 ]
Sanchez-Cordero, V. [5 ]
Rodriguez-Moreno, A. [5 ]
Ludert, J. E. [1 ]
机构
[1] Ctr Res & Adv Studies CINVESTAV IPN, Dept Infect & Mol Pathogenesis, Mexico City, DF, Mexico
[2] Reg Ctr Vector Control, Jojutla, Mexico
[3] INSP Cuernavaca, Ctr Res Infect Dis CISEI, Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico
[4] Vet Clin, Campeche, Mexico
[5] Univ Nacl Autonoma Mexico, Inst Biol, Mexico City, DF, Mexico
关键词
Dengue virus; bats; dengue sylvatic cycle; Mexico; EMERGENCE;
D O I
10.1111/zph.12276
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Bats are reservoirs for viruses with zoonotic potential in the Americas, and scattered evidence exists suggesting that bats may act as reservoirs for dengue virus (DENV). To explore further the role of bats as part of DENV sylvatic cycles, 240 bats of 18 species were captured in 2 states of Mexico with contrasting ecological characteristics but concurrent DENV activity in humans. RT-PCR analysis of RNA extracted from liver or spleen tissue from de bats failed to show evidence for the presence of DENV nucleic acids in these organs. In addition, plasma assayed by plaque reduction neutralization test showed no evidence of neutralizing anti-DENV antibodies. These results suggest that American bats may not be reservoirs or amplification host for DENV infection.
引用
收藏
页码:579 / 583
页数:5
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