Bisabocurcumin, a new skeleton curcuminoid from the rhizomes of Curcuma longa L.

被引:19
|
作者
Xiao, Yun Chuan [1 ]
Xie, Jing [1 ]
Yu, Min [1 ]
Liu, Miao [1 ]
Ran, Jian [1 ]
Xi, Zhen [1 ]
Li, Wei [2 ]
Huang, Jing [1 ]
机构
[1] Sichuan Univ, W China Sch Pharm, Chengdu 610041, Peoples R China
[2] Sichuan Univ, State Key Lab Oral Dis, Chengdu 610041, Peoples R China
关键词
Zingiberaceae; Curcuma longa; Bisabolane-type sesquiterpene; Curcumin; Bisabocurcumin; BISDEMETHOXYCURCUMIN; DEMETHOXYCURCUMIN; ANALOGS;
D O I
10.1016/j.cclet.2011.09.002
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new skeleton bisabolane-type sesquiterpene curcuminoid, bisabocurcumin (1), along with 5 known compounds, curcumin (2), demethoxycurcumin (3), bidemethoxycurcumin (4), (1E,4E)-1,5-bis(4-hydroxy-3-methoxyphenyl)-penta-1,4-dien-3-one (5), and (1E,4E)-1-(4-hydroxy-3-methoxyphenyl)-5-(4-hydroxy phenyl-)-penta-1,4-dien-3-one (6) were isolated from the rhizomes of Curcuma longa L. Their structures were determined on the basis of spectroscopic analysis. Bisabocurcumin (1) is firstly obtained from nature with a new skeleton combined by a bisabolane-type sesquiterpene and a 1,7-diphenylheptanoid through a C-C bond. (C) 2011 Jing Huang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码:1457 / 1460
页数:4
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