A facile solid phase synthesis of 2-alkylthio-4(1H)-quinolones

被引：0

作者：

Tang, J

Wu, MG

Huang, X

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Zhejiang, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2003年 / 21卷 / 05期

关键词：

solid-phase synthesis; resin-bound cyclic malonic acid ester; 2-alkylthio-4(1H)-quinolones;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The resin-bound cyclic malonic acid ester 2 reacted with aryl isothiocyanate and alkyl halides to afford the key intermediate arylthioaminomethylene cyclic malonic ester resin 3. Subsequently, resin 3 proceeded thermal cyclization giving the 2-alkylthio-4(1H)-quinolones in good yields and excellent purities.

引用

页码：585 / 587

页数：3

共 13 条

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