Visual field loss in primary congenital glaucoma

被引:11
作者
Sinha, Gautam [1 ]
Patil, Bharat [1 ]
Sihota, Ramanjit [1 ]
Gupta, Viney [1 ]
Nayak, Bhagabat [1 ]
Sharma, Reetika [1 ]
Sharma, Ajay [1 ]
Gupta, Neeraj [1 ]
机构
[1] All India Inst Med Sci, Dr Rajendra Prasad Ctr Ophthalm Sci, Glaucoma Res Facil & Clin Serv, New Delhi 110029, India
来源
JOURNAL OF AAPOS | 2015年 / 19卷 / 02期
关键词
INTRAOCULAR-PRESSURE; AUTOMATED PERIMETRY; PEDIATRIC POPULATION; NORMATIVE VALUES; CHILDREN; GOLDMANN; DEFECTS; ACUITY;
D O I
10.1016/j.jaapos.2014.12.008
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
PURPOSE To assess the visual field defects in primary congenital glaucoma (PCG) and to identify associated risk factors. METHODS In this cross-sectional study visual fields of consecutive PCG patients were examined using Humphery Field Analyzer (HFA) or Goldmann visual field (GVF). All patients had maintained an intraoaular pressure (TOP) <= 14 mm Hg on standard care. Mean deviation, pattern standard deviation (PSD), foveal threshold in HFA, and global visual field extent (degrees) in 24 meridians for targets V4e, I4e, I2e in GVF were recorded and evaluated with respect to baseline TOP and age at detection. Statistical analysis was performed by Kruskal Wallis and Mann-Whitney test. Qualitative analysis of GVF and reliable fields in HFA was performed. RESULTS A total of 100 eyes of 77 patients were included: 56 eyes of 47 patients were in the HFA group; 44 eyes of 30 patients, in the GVF group. On HFA, mean deviation detected at <= 1 month of age was significantly lower than eyes detected after 1 year (P < 0.001). On GVF, the global visual field extent for target I4e and I2e was significantly lower for PCG detected at <= 1 month of age compared to those seen at >1 year (I4e, P < 0.001; I2e, P = 0.005). Mean deviation, PSD, and foveal threshold were significantly lower in PCG with baseline TOP of >30 mm Hg than with TOP of 20-25 mm Hg (mean deviation, P < 0.001; PSD, P = 0.002; foveal threshold, P = 0.002). Extent for targets V4e and I4e on GVF were significantly lower in patients with baseline TOP of >30 mm Hg compared to those with baseline TOP of 20-25 mm Hg (V4e, P = 0.002; I4e, P = 0.003). Definitive glaucomatous defects were found in 36 eyes (41%), most ommon being arcuate scotoma (19 eyes [22%]). CONCLUSIONS PCG detected at age <= 1 month and those having a baseline TOP of >30 mm Hg show greater visual field loss.
引用
收藏
页码:124 / 129
页数:6
相关论文
共 31 条
  • [1] Agarwal Harish C., 2000, Indian Journal of Ophthalmology, V48, P301
  • [2] Alward WLM, 2000, GLAUCOMA REQUISITES, P56
  • [3] BECK RW, 1985, OPHTHALMOLOGY, V92, P77
  • [4] CEROVSKI B, 1990, Acta Medica Iugoslavica, V44, P549
  • [5] Christopher J.Dickens., 1996, GLAUCOMAS, V2, P729
  • [6] Long-term outcome of primary congenital glaucoma
    de Silva, Don Julian
    Khaw, Peng T.
    Brookes, John L.
    [J]. JOURNAL OF AAPOS, 2011, 15 (02): : 148 - 152
  • [7] de Souza EC, 2000, J PEDIAT OPHTH STRAB, V37, P266
  • [8] Detry-Morel M, 1996, Bull Soc Belge Ophtalmol, V262, P143
  • [9] Prognosis of primary ab externo surgery for primary congenital glaucoma
    Dietlein, TS
    Jacobi, PC
    Krieglstein, GK
    [J]. BRITISH JOURNAL OF OPHTHALMOLOGY, 1999, 83 (03) : 317 - 322
  • [10] Automated perimetry in amblyopia: A generalized depression
    Donahue, SP
    Wall, M
    Kutzko, KE
    Kardon, RH
    [J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 1999, 127 (03) : 312 - 321