Detection of Mycoplasma genitalium-Reactive Cervicovaginal Antibodies among Infected Women

被引:17
作者
Iverson-Cabral, Stefanie L. [1 ,2 ]
Manhart, Lisa E. [3 ]
Totten, Patricia A. [2 ]
机构
[1] Univ Washington, Harborview Med Ctr, Dept Med, Div Infect Dis, Seattle, WA 98104 USA
[2] Univ Washington, Dept Global Hlth, Pathobiol Interdisciplinary Program, Seattle, WA 98104 USA
[3] Univ Washington, Dept Epidemiol, Seattle, WA 98104 USA
关键词
REPETITIVE CHROMOSOMAL SEQUENCES; IMMUNOGLOBULINS; RECOMBINATION; SECRETIONS; URETHRITIS; MGPB; IGA;
D O I
10.1128/CVI.05174-11
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Mycoplasma genitalium-reactive cervicovaginal IgA and IgG antibodies were detected in 51.9% and 70.4% of 27 infected women and 22.2% and 18.5% of 27 uninfected controls, respectively. The predominance of MgpB- and MgpC-reactive antibodies at the site of infection is consistent with their hypothesized role in selecting antigenic variants during persistent infection.
引用
收藏
页码:1783 / 1786
页数:4
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