Nanopore Detection of Cancer Biomarkers: A Challenge to Science

被引：3
作者：
Bhatti, Huma [1 ]
Lu, Zuhong [1 ]
Liu, Quanjun [1 ]
机构：
[1] Southeast Univ, Nanjing, Peoples R China
来源：
TECHNOLOGY IN CANCER RESEARCH & TREATMENT | 2022年 / 21卷
基金：
中国国家自然科学基金; 国家重点研发计划;
关键词：
nanopore; early detection; cancer; cancer biomarkers; screening; diagnosis; CIRCULATING TUMOR DNA; SINGLE-STRANDED-DNA; MICRORNAS; SAMPLES; CELLS; PROBE;
D O I：
10.1177/15330338221076669
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Cancer is the most complex and leading cause of fatality worldwide. Despite meritorious research in the field of cancer, it is still a substantial threat to human life. In this article, we address a question on the present strategies and manifest the importance of critical biomarkers for cancer screening and early diagnosis before the symptoms appear. However, this goal can only be achieved if scientists will focus on ultra-sensitive detection techniques such as "Nanopore." Nanopore sensing is a simple and rapid single-molecule detection technique that can detect multiple cancer biomarkers in femto-Molar concentrations in real time. Last but not least, we propose a systematic policy to win the war against cancer that is a big challenge to science.
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页数：4
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