Guideline on management of suspected adverse reactions to ingested histamine

被引：0

作者：

Reese, I ^{[1
]}

Ballmer-Weber, B. ^{[2
]}

Beyer, K. ^{[3
]}

Doelle-Bierke, S. ^{[4
]}

Kleine-Tebbe, J. ^{[5
]}

Klimek, L. ^{[6
]}

Laemmel, S. ^{[7
]}

Lepp, U. ^{[8
]}

Saloga, J. ^{[9
]}

Schaefer, C. ^{[10
]}

Szepfalusi, Z. ^{[11
]}

Treudler, R. ^{[12
]}

Werfel, T. ^{[13
]}

Zuberbier, T. ^{[14
]}

Worm, M. ^{[4
]}

机构：

[1] Ernahrungstherapie, Munich, Germany

[2] Univ Spital Zurich, Schweiz & Dermatol Klin, Klin Dermatol & Allergol Kantonsspital St Gallen, Zurich, Switzerland

[3] Charite, Campus Virchow Klinikum, Klin Padiatrie Schwerpunkt Pneumol & Immunol, Berlin, Germany

[4] Charite Univ Med Berlin, Allergol & Immunol, Klin Dermatol Venerol & Allergol, Berlin, Germany

[5] Allergie & Asthma Zentrum Westend, Berlin, Germany

[6] Zentrum Rhinol & Allergol, Wiesbaden, Germany

[7] Deutsch Allergie & Asthmabund eV DAAB, Monchengladbach, Germany

[8] Praxis Lungenheilkunde & Allergol, Stade, Germany

[9] Johannes Gutenberg Univ Mainz, Univ Med, Hautklin, Mainz, Germany

[10] Ernahrungstherapie, Schwarzenbek, Germany

[11] Med Univ Wien, Univ Klin Kinder & Jugendheilkunde, Abt Padiatr Pulmol Allergol & Endokrinol, Vienna, Austria

[12] Univ Med Leipzig, Klin Dermatol Venerol & Allergol, Leipzig, Germany

[13] Hannover Med Sch, Klin Dermatol Allergol & Venerol, Hannover, Germany

[14] Charite Univ Med Berlin, Klin Dermatol Venerol & Allergol, Comprehens Allergy Ctr Charite, Berlin, Germany

来源：

ALLERGOLOGIE | 2021年 / 44卷 / 10期

关键词：

adverse reaction to food; histamine intolerance; diamine oxidase; restrictive diet; diet modification; DIAMINE OXIDASE ACTIVITY; BIOGENIC-AMINES; COLONIC-MUCOSA; PLASMA-LEVELS; RECEPTOR; FREE DIET; INTOLERANCE; SERUM; SYMPTOMS; RESPONSES;

D O I：

10.5414/ALX02269

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Adverse reactions to food or food ingredients are more often perceived than objectively verifiable. However, reliable laboratory tests are often lacking. As a result, people with perceived adverse reactions to food often follow extensive elimination diets for years and unnecessarily restrict their diet, as in the case of the frequently suspected histamine intolerance. In this condition, laboratory parameters such as the determination of diamine oxidase in serum have been shown to be inconclusive. The lack of symptom reproducibility calls into question the clinical picture of adverse reactions to ingested histamine. In order to approach persons with perceived histamine intolerance and to support them in moving from blanket restrictions, which are often unnecessarily strict, to effective personalized therapeutic strategies, the present guideline of the Working Group on Food Allergy of the German Society of Allergology and Clinical Immunology (DGAKI) in cooperation with the Medical Association of German Allergists (AeDA), the Pediatric Allergology and Environmental Medicine (GPA) as well as the Swiss Society of Allergology and Immunology (SGAI) and the Austrian Society of Allergology and Immunology (OGAI) recommends a practicable diagnostic and therapeutic approach.

引用

页码：761 / 772

页数：12

共 51 条

[1] INHIBITION OF DIAMINE OXIDASE ACTIVITY BY METRONIDAZOLE [J].