Microwave-Assisted Green Synthesis of Non-Cytotoxic Silver Nanoparticles Using the Aqueous Extract of Rosa santana (rose) Petals and Their Antimicrobial Activity

被引:45
作者
Jahan, Israt [1 ]
Erci, Fatih [2 ]
Isildak, Ibrahim [1 ]
机构
[1] Yildiz Tech Univ, Fac Chem & Met Engn, Dept Bioengn, TR-34210 Istanbul, Turkey
[2] Necmettin Erbakan Univ, Fac Sci, Dept Biotechnol, Meram Konya, Turkey
关键词
Biological activity; microwave-assisted synthesis; Rosa santana; silver nanoparticles; LEAF EXTRACT; GOLD NANOPARTICLES; ANTIBACTERIAL; BIOSYNTHESIS; AG;
D O I
10.1080/00032719.2019.1572179
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Green methods using biological extracts, in particular plant-based solutions, have shown great potential for silver nanoparticle synthesis. A microwave-assisted single-step phytosynthesis of silver nanoparticles is described in the present study. The aqueous extract obtained from the Rosa santana (rose) petals was used for the first time in the synthesis. The synthesized nanoparticles obtained after optimized microwave conditions for time and temperature were analyzed by ultraviolet-visible spectroscopy (UV-Vis), Fourier-transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), and Zeta-size analysis. The results obtained from the characterization studies showed that the synthesized nanoparticles were nearly spherical in shape with sizes from 6.52 nm to 25.24 nm with an average particle size of 14.48 nm with a face-centered cubic structure. The antibacterial activities of the synthesized nanoparticles were evaluated and revealed that the silver nanoparticles displayed good inhibition against both Gram-negative and Gram-positive bacteria. Also, the cytotoxic effect of the silver nanoparticles on a mouse fibroblast cell line (L929) was studied by a cell viability assay. The results showed that phytosynthesized silver nanoparticles were nontoxic to the healthy normal cell line at all tested concentrations.
引用
收藏
页码:1860 / 1873
页数:14
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