Discrete-time survival models with long-term survivors

被引:27
作者
Zhao, Xiaobing [2 ,3 ]
Zhou, Xian [1 ]
机构
[1] Macquarie Univ, Dept Actuarial Studies, N Ryde, NSW, Australia
[2] E China Normal Univ, Dept Stat, Shanghai 200062, Peoples R China
[3] So Yangtze Univ, Sch Sci, Wuxi, Jiangsu Prov, Peoples R China
关键词
discrete time; long-term survivors; cure model; proportional hazards; maximum likelihood estimation; approximate partial likelihood; discrete-time survival models;
D O I
10.1002/sim.3018
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Discrete-time survival data typically possess three features: discreteness, ties, and concomitant information, which require appropriate discrete-time models to analyze. In this paper, we first review some existing discrete-time survival models and then extend them to discrete-time cute survival models, which account for the presence of long-term survivors (cured individuals). The maximum likelihood estimation as well as approximate partial likelihood approaches are used to estimate the model parameters. Simulation results are shown to support the suitability of such models for discrete-time survival data with long-term survivors. An example of applications on a set of bladder tumor recurrence data is also presented. Copyright (c) 2007 John Wiley & Sons, Ltd.
引用
收藏
页码:1261 / 1281
页数:21
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