Automated image analysis of polymer beads and size distribution

被引：7
作者：
Jose, AJ [1 ]
Wong, LS [1 ]
Merrington, J [1 ]
Bradley, M [1 ]
机构：
[1] Univ Southampton, Asahi Kasei Satellite Lab, Sch Chem, Southampton SO17 1BJ, Hants, England
来源：
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH | 2005年 / 44卷 / 23期
关键词：
D O I：
10.1021/ie0495123
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
Size analysis of polymer beads is currently carried out using instruments such as Coulter counters. Here, image analysis software was used to analyze digital pictures of polymer beads and determine size profiles. Analysis was automated to provide high throughput scanning of images, and results compared favorably with traditional laser diffraction measurements. The technique also enabled the roundness of the beads to be measured in order to assess the bead quality after polymerization and physical manipulation. This method enabled automated and high throughput characterization of beads.
引用
收藏
页码：8659 / 8662
页数：4
相关论文
共 18 条
  • [1] Allen T., 1990, PARTICLE SIZE MEASUR, VFourth
  • [2] BARTH HG, 1995, ANAL CHEM, V67, pR257
  • [3] Carai A, 2002, ANTICANCER RES, V22, P3889
  • [4] ETZLER FM, 2002, POLYM MAT SCI ENG, V87, P335
  • [5] Measurement of green fluorescent protein concentration in single cells by image analysis
    Furtado, A
    Henry, R
    [J]. ANALYTICAL BIOCHEMISTRY, 2002, 310 (01) : 84 - 92
  • [6] GARDON JL, 1977, POLYM PROCESS, P143
  • [7] Diffusion of reagents in macrobeads
    Groth, T
    Grotli, M
    Meldal, M
    [J]. JOURNAL OF COMBINATORIAL CHEMISTRY, 2001, 3 (05): : 461 - 468
  • [8] Johnson I, 2001, ENVIRON TOXICOL, V16, P68
  • [9] JOHNSON NL, 1994, CONTINUOUS U DISTRIB, P628
  • [10] MIKES O, 1975, LIQUID COLUMN CHROMA, P69
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