Subependymal giant cell astrocytoma with positive tuberin expression - Case report

被引：13

作者：

Tabuchi, S

Takigawa, H

Oka, A

Mizuguchi, M

Horie, Y

Watanabe, T

机构：

[1] Tottori Univ, Sch Med, Inst Neurol Sci, Dept Neurosurg, Yonago, Tottori 6838504, Japan

[2] Tottori Univ, Sch Med, Inst Neurol Sci, Dept Neuropediat, Yonago, Tottori 6838504, Japan

[3] Tottori Univ, Dept Pathol, Yonago, Tottori 683, Japan

[4] Jichi Med Sch, Dept Pediat, Minami Kawachi, Tochigi, Japan

来源：

NEUROLOGIA MEDICO-CHIRURGICA | 2003年 / 43卷 / 12期

关键词：

subependymal giant cell astrocytoma; tuberous sclerosis complex; TSC; tuberin;

D O I：

10.2176/nmc.43.616

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

An 11-year-old male presented with subependymal giant cell astrocytoma (SEGA) without other manifestations of tuberous sclerosis such as facial angiofibroma, epilepsy, or mental retardation. The diagnosis was "possible tuberous sclerosis complex" (TSC). Total resection of the tumor was performed. Immunohistochemical study revealed positive tuberin expression. In general, loss of tuberin is thought to be critical to the TSC phenotype. Our case demonstrated clear expression of tuberin in the SEGA specimen.

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收藏

页码：616 / 618

页数：3

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