Chemotherapy-associated anemia in patients with lung cancer: an epidemiological, retrospective and multicenter study

被引：5

作者：

Munoz-Langa, Jose ^{[1
]}

De Castro, Javier ^{[2
]}

Gasco, Pere ^{[3
]}

Sanchez, Alfredo ^{[4
]}

Esteban, Emilio ^{[5
]}

Manuel Gasent, Jose ^{[6
]}

Barneto, Isidoro ^{[7
]}

Montalar, Joaquin ^{[8
]}

Artal, Angel ^{[9
]}

Vidal, Sara ^{[10
]}

机构：

[1] Hosp Doctor Peset, Valencia, Spain

[2] Hosp La Paz, Madrid, Spain

[3] Hosp Clin Barcelona, Barcelona, Spain

[4] Hosp Prov Castellon, Castellon de La Plana, Spain

[5] Univ Oviedo, Hosp Cent Asturias, E-33080 Oviedo, Spain

[6] Hosp Marina Alta, Denia, Spain

[7] Hosp Reina Sofia, Murcia, Spain

[8] Hosp La Fe, E-46009 Valencia, Spain

[9] Hosp Miguel Servet, Zaragoza, Spain

[10] Jansssen Cilag, Madrid, Spain

来源：

FUTURE ONCOLOGY | 2015年 / 11卷 / 11期

关键词：

anemia; chemotherapy; erythropoietin-stimulating agents; iron; lung cancer; transfusion; DARBEPOETIN ALPHA; HEMOGLOBIN LEVELS; MANAGEMENT; CARCINOMA; SURVIVAL; BENEFITS; IMPACT;

D O I：

10.2217/fon.15.75

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aim: The aim of the Anaemia in Lung Cancer in Spain study was to provide epidemiological data and treatment of anemia in 349 lung cancer patients undergoing first-line chemotherapy. Methods: The prevalence of anemia (hemoglobin level <12 g/dl) was 18.3% and the incidence 80.7%. Mean hemoglobin levels were 13.4 g/dl (95% CI: 13.2-13.6) and 11.5 g/dl (95% CI: 11.3-11.7) at the starting and at the end of chemotherapy, respectively. Of the 294 patients with anemia, 174 (59.2%) were treated. Results: Erythropoiesis-stimulating agents were given to 90.2% patients, alone in 31.6% and combined iron in 39.7%, transfusion in 9.2% and iron and transfusion in 9.8%. Conclusion: These results suggest an appropriate and rational use of erythropoiesis-stimulating agents in the treatment of chemotherapy-associated anemia in lung cancer patients.

引用

页码：1665 / 1674

页数：10

共 22 条

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