A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

被引：34
作者：
Allin, SM
Northfield, CJ
Page, MI [1 ]
Slawin, AMZ
机构：
[1] Loughborough Univ Technol, Dept Chem, Loughborough LE11 3TU, Leics, England
[2] Univ Huddersfield, Dept Chem & Biol Sci, Huddersfield HD1 3DH, W Yorkshire, England
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 01期
关键词：
amino alcohols; aminals; stereocontrol; transition states; nitrogen heterocycles;
D O I：
10.1016/S0040-4039(98)80041-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic gamma-lactam substrate as an N-acyliminium ion precursor. (C) 1998 Elsevier Science Ltd. All rights reserved.
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收藏
页码：141 / 142
页数：2
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