Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review

被引：217
作者：
Minzanova, Salima T. [1 ]
Mironov, Vladimir F. [1 ]
Arkhipova, Daria M. [1 ]
Khabibullina, Anna V. [1 ]
Mironova, Lubov G. [1 ]
Zakirova, Yulia M. [2 ]
Milyukov, Vasili A. [1 ]
机构：
[1] Russian Acad Sci, Arbuzov Inst Organ & Phys Chem, FRC Kazan Sci Ctr, Kazan 420088, Russia
[2] Kazan Univ, KFU, Kazan Volga Reg Fed Univ, Kazan 420008, Russia
来源：
POLYMERS | 2018年 / 10卷 / 12期
关键词：
pectin; modified pectin; biological activity; drug delivery; pharmaceutical; CANCER CELL-PROLIFERATION; HIGH METHOXYL PECTIN; SWEET-POTATO PECTIN; IN-VITRO; CITRUS PECTIN; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT CAPACITY; ILEX-PARAGUARIENSIS; ASSISTED EXTRACTION; IMMUNOMODULATING PECTINS;
D O I：
10.3390/polym10121407
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Pectin is a polymer with a core of alternating -1,4-linked d-galacturonic acid and -1,2-l-rhamnose units, as well as a variety of neutral sugars such as arabinose, galactose, and lesser amounts of other sugars. Currently, native pectins have been compared to modified ones due to the development of natural medicines and health products. In this review, the results of a study of the bioactivity of pectic polysaccharides, including its various pharmacological applications, such as its immunoregulatory, anti-inflammatory, hypoglycemic, antibacterial, antioxidant and antitumor activities, have been summarized. The potential of pectins to contribute to the enhancement of drug delivery systems has been observed.
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页数：31
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