Pregnancy and Breastfeeding in Inflammatory Bowel Disease

被引：14

作者：

Biedermann, Luc ^{[1
]}

Rogler, Gerhard ^{[1
,2
]}

Vavricka, Stephan R. ^{[1
,2
,3
]}

Seibold, Frank ^{[4
]}

Seirafi, Mariam ^{[5
]}

机构：

[1] Univ Zurich Hosp, Div Gastroenterol & Hepatol, CH-8091 Zurich, Switzerland

[2] Univ Zurich, Zurich Ctr Integrat Human Physiol, Zurich, Switzerland

[3] Triemli Municipal Hosp, Div Gastroenterol & Hepatol, Zurich, Switzerland

[4] Spital Netz Bern, Hosp Tiefenau, Div Gastroenterol & Hepatol, Bern, Switzerland

[5] Univ Hosp Geneva, Div Gastroenterol & Hepatol, Geneva, Switzerland

来源：

DIGESTION | 2012年 / 86卷

基金：

瑞士国家科学基金会;

关键词：

Pregnancy; Breastfeeding; Medical therapy benefits; POUCH-ANAL ANASTOMOSIS; CROHNS-DISEASE; ULCERATIVE-COLITIS; 5-AMINOSALICYLIC ACID; MALE-INFERTILITY; BIRTH OUTCOMES; RISK-FACTOR; WOMEN; AZATHIOPRINE; FERTILITY;

D O I：

10.1159/000341941

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Inflammatory bowel disease (IBD) is frequent in women during their peak reproductive years. Accordingly, a significant number of questions and uncertainties arise from this population regarding the risk of transmission of IBD to the offspring, the impact of the disease and therapies on the fertility, the role of the disease on the course of the pregnancy and the mode of delivery, the impact of the therapy on the pregnancy and fetal development as well as breastfeeding. The safety of medical therapy during pregnancy and lactation is a major concern for both pregnant women and their partners as well as for physicians. As a general rule, it can be stated that the benefit of continuing medical therapy in IBD during pregnancy outweighs the potential risks in the vast majority of instances. This article will review recent developments on this topic consistent with the European Crohn's and Colitis Organization guidelines. Copyright (C) 2012 S. Karger AG, Basel

引用

页码：45 / 54

页数：10

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