The antibacterial activity of plaunotol against Staphylococcus aureus isolated from the skin of patients with atopic dermatitis

被引:0
作者
Matsumoto, Y
Hamashima, H
Masuda, K
Shiojima, K
Sasatsu, M [1 ]
Arai, T
机构
[1] Showa Coll Pharmaceut Sci, Dept Microbiol, Tokyo 1948543, Japan
[2] Showa Coll Pharmaceut Sci, Dept Phytochem, Tokyo 1948543, Japan
关键词
plaunotol; antibacterial activity; atopic dermatitis; skin care; methicillin-resistant Staphylococcus aureus;
D O I
暂无
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Plaunotol was tested for possible antibacterial activity against twenty strains of methicillin-resistant Staphylococcus aureus (MRSA) and fourteen strains of methicillin-sensitive S. aureus (MSSA) which had been isolated from the skin of patients with atopic dermatitis under growth-promoting conditions. Plaunotol was effective against all strains tested. The dose of plaunotol for 50% inhibition of growth (ID50) ranged from 2.5 to 16 mu g/ml for strains of MRSA and from 2.5 to 7.0 mu g/ml for those of MSSA. These results suggest that plaunotol may be useful in the prevention of infection by MRSA and in skin care for patients with atopic dermatitis.
引用
收藏
页码:149 / 155
页数:7
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