Primary central nervous system lymphoma

被引：25
作者：
Batchelor, Tracy T. [1 ,2 ,3 ]
机构：
[1] Massachusetts Gen Hosp, Ctr Canc, Div Hematol Oncol, Dept Neurol, Boston, MA USA
[2] Massachusetts Gen Hosp, Ctr Canc, Div Hematol Oncol, Dept Radiat Oncol, Boston, MA USA
[3] Harvard Med Sch, Boston, MA USA
来源：
HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM | 2016年
基金：
英国医学研究理事会;
关键词：
PRIMARY CNS LYMPHOMA; HIGH-DOSE METHOTREXATE; RECURRENT PRIMARY CNS; WHOLE-BRAIN RADIOTHERAPY; INTENSIVE CHEMOTHERAPY; ELDERLY-PATIENTS; RITUXIMAB; PROCARBAZINE; VINCRISTINE; RADIATION;
D O I：
10.1182/asheducation-2016.1.379
中图分类号：
G40 [教育学];
学科分类号：
040101 ; 120403 ;
摘要：
Primary central nervous system lymphoma (PCNSL) is an extranodal non-Hodgkin lymphoma (NHL) confined to the brain, leptomeninges, eyes, or spinal cord. The majority of PCNSL cases occur in the immunocompetent host, the focus of this review. The prognosis of PCNSL is inferior to that of other NHL subtypes including other organ-specific subtypes of extranodal NHL. The 5-and 10-year survival proportions for PCNSL are 29.3% and 21.6%, respectively. The diagnosis and management of PCNSL differs from that of other primary brain cancers and NHL in other parts of the body.
引用
收藏
页码：379 / 385
页数：7
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