In Vitro Inhibition of Adhesion of Escherichia coli Strains by Xylitol

被引：8

作者：

da Silva, Annelisa Farah ^{[1
]}

Suzuki, Erika Yoko ^{[1
]}

Ferreira, Aline Siqueira ^{[1
]}

Oliveira, Murilo Gomes ^{[1
]}

da Silva, Silvio Silverio ^{[2
,3
]}

Barbosa Raposo, Nadia Rezende ^{[1
,4
]}

机构：

[1] Univ Fed Juiz de Fora, Fac Farm, BR-36036330 Juiz De Fora, MG, Brazil

[2] Univ Sao Paulo, Escola Engn Lorena, Dept Biotecnol, BR-12602810 Lorena, SP, Brazil

[3] Fac Integradas Teresa Avila, BR-12606580 Lorena, SP, Brazil

[4] Univ Sao Paulo, Fac Med, Lab Neurociencias, Sao Paulo, Brazil

来源：

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY | 2011年 / 54卷 / 02期

基金：

巴西圣保罗研究基金会;

关键词：

Bacterial adhesion; Escherichia coli; Scanning electron microscopy; Xylitol; FUTURE ANTIADHESION DRUGS; BACTERIAL DISEASES; AERATION RATE; ADHERENCE; CELLS;

D O I：

10.1590/S1516-89132011000200003

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The present study aimed to evaluate xylitol's antimicrobial and anti-adherence activities on Escherichia coli (ATCC 8739) and on another clinical strain enteropathogenic E. coli (EPEC). In vitro minimum inhibitory concentration (MIC) test and adhesion assays were performed using 0.5, 2.5 and 5.0% xylitol. It was found that xylitol did not have antimicrobial properties on these strains. The scanning electron microscopy (SEM) demonstrated that the slides treated with xylitol had a significant reduction in the number of bacilli and the inhibition of microbial adhesion was probably the xylitol's mechanism of action. Xylitol could be a possible alternative on the control of E. coli infections.

引用

页码：235 / 241

页数：7

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