The purpose of this study is to reflect on the contributions of the work of M. Barrios Casares in the new hermeneutic context in which Nietzschean studies currently find themselves. The thread of the study is based on the latest publication by the Sevillean philosopher, Tentativas sobre Nietzsche (2019), the fundamental lines of which are analysed here. The second objective of this work is to point out some links between this latest publication and the work carried out previously by M. Barrios in the field of translation, editing and essay.