共 10 条
UNCovering the Molecular Machinery of Dependence Receptor Signaling
被引:4
作者:

Bagri, Anil
论文数: 0 引用数: 0
h-index: 0
机构:
Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USA

Ashkenazi, Avi
论文数: 0 引用数: 0
h-index: 0
机构:
Genentech Inc, San Francisco, CA 94080 USA Genentech Inc, San Francisco, CA 94080 USA
机构:
[1] Genentech Inc, San Francisco, CA 94080 USA
关键词:
CANCER;
SYSTEM;
NETRIN;
DEATH;
D O I:
10.1016/j.molcel.2010.12.015
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Dependence receptors send opposite signals in the presence or absence of ligand, but the underlying mechanisms have been elusive. In this issue of Molecular Cell, Guenebeaud et al. (2010) elucidate the molecular signaling machinery of the dependence receptor UNC5B.
引用
收藏
页码:851 / 853
页数:3
相关论文
共 10 条
[1]
Death receptors: Signaling and modulation
[J].
Ashkenazi, A
;
Dixit, VM
.
SCIENCE,
1998, 281 (5381)
:1305-1308

Ashkenazi, A
论文数: 0 引用数: 0
h-index: 0
机构:
Genentech Inc, Dept Mol Oncol, S San Francisco, CA 94080 USA Genentech Inc, Dept Mol Oncol, S San Francisco, CA 94080 USA

Dixit, VM
论文数: 0 引用数: 0
h-index: 0
机构:
Genentech Inc, Dept Mol Oncol, S San Francisco, CA 94080 USA Genentech Inc, Dept Mol Oncol, S San Francisco, CA 94080 USA
[2]
Netrin and DCC: Axon Guidance Regulators at the Intersection of Nervous System Development and Cancer
[J].
Duman-Scheel, M.
.
CURRENT DRUG TARGETS,
2009, 10 (07)
:602-610

Duman-Scheel, M.
论文数: 0 引用数: 0
h-index: 0
机构:
Indiana Univ, Sch Med S Bend Notre Dame, South Bend, IN 46617 USA
Univ Notre Dame, Dept Biol Sci, Walther Canc Inst, Notre Dame, IN 46556 USA
Eck Inst Global Hlth, Notre Dame, IN 46556 USA Indiana Univ, Sch Med S Bend Notre Dame, South Bend, IN 46617 USA
[3]
Dependence receptors: a new paradigm in cell signaling and cancer therapy
[J].
Goldschneider, D.
;
Mehlen, P.
.
ONCOGENE,
2010, 29 (13)
:1865-1882

Goldschneider, D.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, Canc & Dev Lab, Equipe Labellisee La Ligue,CNRS,UMR5238, F-69008 Lyon, Rhone, France Univ Lyon, Ctr Leon Berard, Canc & Dev Lab, Equipe Labellisee La Ligue,CNRS,UMR5238, F-69008 Lyon, Rhone, France

Mehlen, P.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, Canc & Dev Lab, Equipe Labellisee La Ligue,CNRS,UMR5238, F-69008 Lyon, Rhone, France Univ Lyon, Ctr Leon Berard, Canc & Dev Lab, Equipe Labellisee La Ligue,CNRS,UMR5238, F-69008 Lyon, Rhone, France
[4]
DAPk protein family and cancer
[J].
Gozuacik, Devrim
;
Kimchi, Adi
.
AUTOPHAGY,
2006, 2 (02)
:74-79

Gozuacik, Devrim
论文数: 0 引用数: 0
h-index: 0
机构:
Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel

论文数: 引用数:
h-index:
机构:
[5]
The Dependence Receptor UNC5H2/B Triggers Apoptosis via PP2A-Mediated Dephosphorylation of DAP Kinase
[J].
Guenebeaud, Celine
;
Goldschneider, David
;
Castets, Marie
;
Guix, Catherine
;
Chazot, Guillaume
;
Delloye-Bourgeois, Celine
;
Eisenberg-Lerner, Avital
;
Shohat, Galit
;
Zhang, Mingjie
;
Laudet, Vincent
;
Kimchi, Adi
;
Bernet, Agnes
;
Mehlen, Patrick
.
MOLECULAR CELL,
2010, 40 (06)
:863-876

Guenebeaud, Celine
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Goldschneider, David
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Castets, Marie
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Guix, Catherine
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Chazot, Guillaume
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Delloye-Bourgeois, Celine
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Eisenberg-Lerner, Avital
论文数: 0 引用数: 0
h-index: 0
机构:
Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Shohat, Galit
论文数: 0 引用数: 0
h-index: 0
机构:
Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Zhang, Mingjie
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Mol Neurosci Ctr, Div Life Sci, Hong Kong, Hong Kong, Peoples R China Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Laudet, Vincent
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ecole Normale Super Lyon, INRA BioSci Lyon Gerland IFR128, Inst Genom Fonct Lyon,CNRS UMR5242, F-69364 Lyon 07, France Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

论文数: 引用数:
h-index:
机构:

Bernet, Agnes
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France

Mehlen, Patrick
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France Univ Lyon, Ctr Leon Berard, CNRS UMR5238, Apoptosis Canc & Dev Lab,Equipe Labellisee La Lig, F-69008 Lyon, France
[6]
The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase
[J].
Llambi, F
;
Calheiros-Lourenço, F
;
Gozuacik, D
;
Guix, C
;
Pays, L
;
Del Rio, G
;
Kimchi, A
;
Mehlen, P
.
EMBO JOURNAL,
2005, 24 (06)
:1192-1201

Llambi, F
论文数: 0 引用数: 0
h-index: 0
机构: Ctr Leon Berard, CNRS, FRE2870, Apoptosis Canc & Dev Lab,Equipe Labellisee Ligue, F-69373 Lyon, France

Calheiros-Lourenço, F
论文数: 0 引用数: 0
h-index: 0
机构: Ctr Leon Berard, CNRS, FRE2870, Apoptosis Canc & Dev Lab,Equipe Labellisee Ligue, F-69373 Lyon, France

Gozuacik, D
论文数: 0 引用数: 0
h-index: 0
机构: Ctr Leon Berard, CNRS, FRE2870, Apoptosis Canc & Dev Lab,Equipe Labellisee Ligue, F-69373 Lyon, France

Guix, C
论文数: 0 引用数: 0
h-index: 0
机构: Ctr Leon Berard, CNRS, FRE2870, Apoptosis Canc & Dev Lab,Equipe Labellisee Ligue, F-69373 Lyon, France

Pays, L
论文数: 0 引用数: 0
h-index: 0
机构: Ctr Leon Berard, CNRS, FRE2870, Apoptosis Canc & Dev Lab,Equipe Labellisee Ligue, F-69373 Lyon, France

Del Rio, G
论文数: 0 引用数: 0
h-index: 0
机构: Ctr Leon Berard, CNRS, FRE2870, Apoptosis Canc & Dev Lab,Equipe Labellisee Ligue, F-69373 Lyon, France

论文数: 引用数:
h-index:
机构:

Mehlen, P
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Leon Berard, CNRS, FRE2870, Apoptosis Canc & Dev Lab,Equipe Labellisee Ligue, F-69373 Lyon, France Ctr Leon Berard, CNRS, FRE2870, Apoptosis Canc & Dev Lab,Equipe Labellisee Ligue, F-69373 Lyon, France
[7]
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system (Publication with Expression of Concern)
[J].
Lu, XW
;
le Noble, F
;
Yuan, L
;
Jiang, QJ
;
de Lafarge, B
;
Sugiyama, D
;
Bréant, C
;
Claes, F
;
De Smet, F
;
Thomas, JL
;
Autiero, M
;
Carmeliet, P
;
Tessier-Lavigne, M
;
Eichmann, A
.
NATURE,
2004, 432 (7014)
:179-186

Lu, XW
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

le Noble, F
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Yuan, L
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Jiang, QJ
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

de Lafarge, B
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Sugiyama, D
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Bréant, C
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Claes, F
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

De Smet, F
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Thomas, JL
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Autiero, M
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Carmeliet, P
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Tessier-Lavigne, M
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France

Eichmann, A
论文数: 0 引用数: 0
h-index: 0
机构: Coll France, INSERM, U36, F-75005 Paris, France
[8]
Dependence receptors: between life and death
[J].
Mehlen, P
;
Thibert, C
.
CELLULAR AND MOLECULAR LIFE SCIENCES,
2004, 61 (15)
:1854-1866

Mehlen, P
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Lyon, CNRS,UMR 5534, Apoptosis Differentiat Lab, Equipe Labelisee La Ligue,Mol & Cellular Genet Ct, F-69622 Villeurbanne, France Univ Lyon, CNRS,UMR 5534, Apoptosis Differentiat Lab, Equipe Labelisee La Ligue,Mol & Cellular Genet Ct, F-69622 Villeurbanne, France

Thibert, C
论文数: 0 引用数: 0
h-index: 0
机构: Univ Lyon, CNRS,UMR 5534, Apoptosis Differentiat Lab, Equipe Labelisee La Ligue,Mol & Cellular Genet Ct, F-69622 Villeurbanne, France
[9]
Arterial-Venous Specification During Development
[J].
Swift, Matthew R.
;
Weinstein, Brant M.
.
CIRCULATION RESEARCH,
2009, 104 (05)
:576-588

Swift, Matthew R.
论文数: 0 引用数: 0
h-index: 0
机构:
NICHHD, Mol Genet Lab, NIH, Bethesda, MD 20892 USA NICHHD, Mol Genet Lab, NIH, Bethesda, MD 20892 USA

Weinstein, Brant M.
论文数: 0 引用数: 0
h-index: 0
机构:
NICHHD, Mol Genet Lab, NIH, Bethesda, MD 20892 USA NICHHD, Mol Genet Lab, NIH, Bethesda, MD 20892 USA
[10]
Autoinhibition of UNC5b Revealed by the Cytoplasmic Domain Structure of the Receptor
[J].
Wang, Rui
;
Wei, Zhiyi
;
Jin, Hao
;
Wu, Hao
;
Yu, Cong
;
Wen, Wenyu
;
Chan, Ling-Nga
;
Wen, Zilong
;
Zhang, Mingjie
.
MOLECULAR CELL,
2009, 33 (06)
:692-703

Wang, Rui
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China

Wei, Zhiyi
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China

Jin, Hao
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China

Wu, Hao
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China

Yu, Cong
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China

Wen, Wenyu
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China

Chan, Ling-Nga
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China

Wen, Zilong
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China

Zhang, Mingjie
论文数: 0 引用数: 0
h-index: 0
机构:
Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China Hong Kong Univ Sci & Technol, Dept Biochem, Mol Neurosci Sect, Kowloon, Hong Kong, Peoples R China