UNCovering the Molecular Machinery of Dependence Receptor Signaling

被引:4
作者
Bagri, Anil [1 ]
Ashkenazi, Avi [1 ]
机构
[1] Genentech Inc, San Francisco, CA 94080 USA
关键词
CANCER; SYSTEM; NETRIN; DEATH;
D O I
10.1016/j.molcel.2010.12.015
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Dependence receptors send opposite signals in the presence or absence of ligand, but the underlying mechanisms have been elusive. In this issue of Molecular Cell, Guenebeaud et al. (2010) elucidate the molecular signaling machinery of the dependence receptor UNC5B.
引用
收藏
页码:851 / 853
页数:3
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